National Institute of Environmental Health Sciences (NIEHS)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Environmental Health Sciences (NIEHS) sits in the top decile of US sponsors by registered trial count (#194 of 15,742 sponsors by registered trial count).

145 total trials 15 currently recruiting 124 completed early-phase tilt top decile by trial count

National Institute of Environmental Health Sciences (NIEHS): 145 sponsored US clinical trials, 15 recruiting.

National Institute of Environmental Health Sciences (NIEHS) sponsors 145 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 124 completed. 3 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 8 trials.

Top-decile sponsor footprint

National Institute of Environmental Health Sciences (NIEHS) ranks in the top decile of sponsors by registered trial count (#194 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 88/100

124 of 125 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (99.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

145 total, page 1 of 3

RECRUITING Phase 2

FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)

NCT07111065

RECRUITING Phase 2

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

NCT06325696

RECRUITING

NIEHS Repository of Stored Biological Samples for Future Use

NCT05666739

RECRUITING

Observation of Environment and Reproductive-Endocrine Effects

NCT06280807

RECRUITING

Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equity

NCT04983251

RECRUITING

Natural History of the Human Biological Response to Environmental Exposure and Injury

NCT04888923

RECRUITING

Reproductive Axis Maturation in the Early Post-Menarchal Years

NCT03986021

RECRUITING

Investigating the Impact of Obesity on Pubertal Development in Girls

NCT02583646

RECRUITING

NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

NCT02327897

RECRUITING

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

NCT01143480

RECRUITING

Inherited Reproductive Disorders

NCT01500447

RECRUITING

Environmental Risk Factors for the Anti-synthetase Syndrome

NCT01276470

RECRUITING

Personalized Environment and Genes Study

NCT00341237

RECRUITING

Immune Cell Response to Stimuli

NCT00397280

RECRUITING

Adult and Juvenile Myositis

NCT00017914

ACTIVE NOT RECRUITING

Factors Influencing Fertility or Pregnancy Health

NCT04595760

ACTIVE NOT RECRUITING

Gulf Long-Term Follow-Up Study

NCT01287000

NOT YET RECRUITING

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

NCT06991751

NOT YET RECRUITING

Stress, Coping, and Sleep Health Study

NCT07566481

NOT YET RECRUITING

A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity

NCT07437976

COMPLETED Phase 2

The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial

NCT05050916

COMPLETED

Serological Surveillance for COVID-19 in Central North Carolina

NCT04490174

COMPLETED

Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19

NCT04403386

COMPLETED

Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function

NCT02743468

COMPLETED

Study of Exposure to Chemicals in Consumer Products

NCT02471365

COMPLETED

Qualitative Assessment of the Work-Sleep Relationship

NCT03389828

COMPLETED Phase 2

Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis

NCT03267277

COMPLETED NA

CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

NCT02858336

COMPLETED

Environmental Risk Factors for Myositis in Military Personnel

NCT01734369

COMPLETED

Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity

NCT01780155

COMPLETED

The COX-2 Gene and the Immune System

NCT01678222

COMPLETED

Environmental Polymorphisms Registry Health and Exposures Survey

NCT01688986

COMPLETED Phase 1

Bisphenol A Controlled Exposure Study

NCT01573429

COMPLETED

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

NCT01143519

COMPLETED

Hormonal Regulation of Puberty and Fertility

NCT01511588

COMPLETED

TGF-(Beta) and Susceptibility to RSV

NCT01224691

COMPLETED

Blood Vessel Study

NCT01524549

COMPLETED

Agricultural Health Study Follow-up

NCT01399411

COMPLETED

The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease

NCT01143493

COMPLETED

A Follow-up of the Early Pregnancy Study Cohort.

NCT01132924

COMPLETED

Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing

NCT01087307

COMPLETED Phase 3

Indoor Woodsmoke PM and Asthma

NCT00807183

COMPLETED

Functional Implications of TNF

NCT00729131

COMPLETED

Lung Mucus Hypersecretion and NQO1

NCT00729352

COMPLETED

Biomarker Analysis of Stress

NCT00527384

COMPLETED

PCOS Twin Study - Environmental Factors in the Development of Polycystic Ovary Syndrome, Phase 2

NCT00444288

COMPLETED

Oral Bacteria and Allergic Disease in Children

NCT00438646

COMPLETED

Children With Asthma in New Orleans After Hurricane Katrina

NCT00426634

COMPLETED

The Influence of Breast Cancer Risk and Risk Perception on Lifestyle Behaviors Among Women With a Family History: A Mixed Method Approach

NCT00393406

COMPLETED

Confirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort

NCT00377351

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3

What is open in the National Institute of Environmental Health Sciences (NIEHS) pipeline

15 recruiting of 145 indexed (10% open); 124 completed (86%).

Phase mix: 3 late (III/IV) vs 7 early (I/II) (early-phase heavy).

Top condition: Asthma (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Environmental Health Sciences (NIEHS): open-pipeline peers nationwide

Peers matched on 145 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300 0%5%10%15% Total trials Recruiting share National Institute of Environmental Health Sciences (NIEHS)Forest LaboratoriesHealthPartners InstituteMylan PharmaceuticalsSCRI Development InnovationsCalifornia Pacific Medical Center Research InstituteUniversity of Rhode IslandSWOG Cancer Research NetworkUniversity of Mississippi Medical Center
National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 145 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this National Institute of Environmental Health Sciences (NIEHS) page

145 registered trials is a research-attention snapshot, not an endorsement of National Institute of Environmental Health Sciences (NIEHS) or any single study.

  • 15 of National Institute of Environmental Health Sciences (NIEHS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Asthma is the condition National Institute of Environmental Health Sciences (NIEHS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Asthma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute of Environmental Health Sciences (NIEHS) pipeline card: 145 registered trials from official public datasets.Report a data error.