National Institute of Environmental Health Sciences (NIEHS)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Environmental Health Sciences (NIEHS) sits in the top decile of US sponsors by registered trial count (#194 of 15,742 sponsors by registered trial count).

145 total trials 15 currently recruiting 124 completed early-phase tilt top decile by trial count

National Institute of Environmental Health Sciences (NIEHS): 145 sponsored US clinical trials, 15 recruiting.

National Institute of Environmental Health Sciences (NIEHS) sponsors 145 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 124 completed. 3 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 8 trials.

Top-decile sponsor footprint

National Institute of Environmental Health Sciences (NIEHS) ranks in the top decile of sponsors by registered trial count (#194 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 88/100

124 of 125 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (99.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

145 total, page 3 of 3

COMPLETED

Molecular Epidemiology of Parkinson's Disease

NCT00042107

COMPLETED NA

Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity

NCT00041821

COMPLETED

Brain Neoplasms, Leukemia and Petrochemical Exposures

NCT00042445

COMPLETED NA

Reducing Pesticide Exposure in Minority Families

NCT00014807

COMPLETED

Incidence and Mortality of Childhood Cancer Among Children of Farmer Pesticide Applications

NCT00339378

COMPLETED NA

Social Network Based Intervention to Reduce Lead Exposure Among Native American Children

NCT00011661

COMPLETED

Asthma Severity in Children and Environmental Agents

NCT00042705

COMPLETED

Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele

NCT00044369

COMPLETED

Vulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.

NCT00044603

COMPLETED

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

NCT00011713

COMPLETED

Cardiac Vulnerability in Potentially Susceptible Patients

NCT00012493

COMPLETED NA

Effects of Pesticide Exposure on Neurodevelopment/Growth/Respiratory Health

NCT00021658

COMPLETED

Study for Future Families

NCT00011687

COMPLETED

Ozone and Rhinovirus-Induced Disease in Asthmatics

NCT00013715

COMPLETED

Fluorescence Bronchoscopy and Molecular Characterization of Abnormal Bronchial Lesions: Novel Approaches for Early Detection of Lung Cancer in High Risk Patients

NCT00512642

COMPLETED

Collaborative Study of 1,3 Butadiene Biomarkers

NCT00023140

COMPLETED

Attention Deficit Disorder and Exposure to Lead

NCT00014898

COMPLETED

Cardiopulmonary Effects of Particulate Exposure

NCT00011310

COMPLETED

Pesticide Exposure and Health Status in North Carolina African American Male Farmers and Farm Workers

NCT00341965

COMPLETED

Stachybotrys Induced Hemorrhage in the Developing Lung

NCT00011700

COMPLETED

Pollutant Altered Allergic Responses

NCT00011440

COMPLETED

Air Pollution and Implantable Cardioverter Defibrillators

NCT00015574

COMPLETED

Lead Exposure, Genetics, and Osteoporosis Epidemiology

NCT00013637

COMPLETED

Cardiovascular Vulnerability to Particulate Exposure

NCT00013949

COMPLETED

Ozone Exposure and Dose Delivered to Human Lungs

NCT00013780

COMPLETED

Protection Against Benzene Toxicity

NCT00011453

COMPLETED

National Survey of Lead and Allergen Hazards in Housing

NCT00339573

COMPLETED

Bladder Cancer Case Control Study of Arsenic in Water

NCT00011518

COMPLETED NA

Community-Based Environmental Health Intervention

NCT00015600

COMPLETED

Health Effects of Early-Life Exposure to Urban Pollutants in Minority Children

NCT00043498

COMPLETED

Johnston County ADHD Study: Environmental, Reporductive, and Familial Risk Factors for Attention-Deficit Hyperactivity Disorder (ADHD)

NCT00339729

COMPLETED

Early Exposure to Lead and Adolescent Development

NCT00011674

COMPLETED

Hormonal and Environmental Risk Factors for Developing Systemic Lupus Erythematosus: The Carolina Lupus (CLU) Study

NCT00342095

COMPLETED

Pesticides--Health Fertility and Reproductive Risk

NCT00015561

COMPLETED

Risk Factors for Uterine Fibroids: A Case Control Study

NCT00339547

COMPLETED

Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study)

NCT00015587

COMPLETED

Dichloroacetate Kinetics, Metabolism and Toxicology

NCT00015015

COMPLETED Phase 3

Treatment of Lead-Exposed Children Trial

NCT00342849

COMPLETED

Estrogen Receptor Gene Mutations

NCT00342498

COMPLETED

Mechanisms of Inflammatory Liver Injury

NCT00011284

COMPLETED

Biomarkers of Benzene Exposure in Inner City Residents

NCT00014963

COMPLETED Phase 3

Nevada Environmental Tobacco Smoke and Health Study

NCT00046306

COMPLETED NA

Reducing Indoor Allergen Exposures in Northern Manhattan and the South Bronx

NCT00023127

COMPLETED

Mohawk Culture, Behavior, Toxicant Exposure and Health

NCT00043238

COMPLETED NA

Community Organizing Network for Environmental Health

NCT00042484

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3

What is open in the National Institute of Environmental Health Sciences (NIEHS) pipeline

15 recruiting of 145 indexed (10% open); 124 completed (86%).

Phase mix: 3 late (III/IV) vs 7 early (I/II) (early-phase heavy).

Top condition: Asthma (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Environmental Health Sciences (NIEHS): open-pipeline peers nationwide

Peers matched on 145 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300 0%5%10%15% Total trials Recruiting share National Institute of Environmental Health Sciences (NIEHS)Forest LaboratoriesHealthPartners InstituteMylan PharmaceuticalsSCRI Development InnovationsCalifornia Pacific Medical Center Research InstituteUniversity of Rhode IslandSWOG Cancer Research NetworkUniversity of Mississippi Medical Center
National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 145 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this National Institute of Environmental Health Sciences (NIEHS) page

145 registered trials is a research-attention snapshot, not an endorsement of National Institute of Environmental Health Sciences (NIEHS) or any single study.

  • 15 of National Institute of Environmental Health Sciences (NIEHS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Asthma is the condition National Institute of Environmental Health Sciences (NIEHS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Asthma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute of Environmental Health Sciences (NIEHS) pipeline card: 145 registered trials from official public datasets.Report a data error.