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NCT00012480 · ClinicalTrials.gov registry record

Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

A clinical trial of Male Infertility and Lead Poisoning, sponsored by National Institute of Environmental Health Sciences (NIEHS).

Completed
Registry status
400
Enrollment target
3
Study locations

NCT00012480 is a study of Male Infertility and Lead Poisoning that has completed, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 400 participants, below the 508-participant average among 8 other Male Infertility trials with a reported enrollment target (21% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT00012480, a study of Male Infertility and Lead Poisoning, has completed, sponsored by National Institute of Environmental Health Sciences (NIEHS).

COMPLETED
Registry status
400 participants
Enrollment target
3
Study locations

Study Summary

Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in men acting as semen donors in an artificial insemination program and in men representative of the general public. Our goal is to identify the mechanism(s) underlying lead's anti-fertility action.

Study Locations (3)

California

  • University of Southern California Women's and Children's Hospital - Los Angeles

New York

  • North Shore University Hospital - Manhasset

Pennsylvania

  • Copper Hospital and Fertility Testing Laboratory and Sperm Bank - Philadelphia

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2002-08
Est. Completion 2007-07

What the Registry Record Tells You About NCT00012480

The ClinicalTrials.gov registry entry for NCT00012480 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 508-participant average among 8 other Male Infertility trials with a reported enrollment target (21% lower). The listed sponsor is National Institute of Environmental Health Sciences (NIEHS), which has 145 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Male Infertility appearing as the primary indexed condition, and to 0 interventions.

NCT00012480 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, New York, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT00012480 about?

NCT00012480 is a clinical study titled "Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm". Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in ...

What is the current status of trial NCT00012480?

This trial is currently completed. The enrollment target is 400 participants. The study started on 2002-08. Estimated completion is 2007-07.

What conditions does trial NCT00012480 study?

This clinical trial studies the following conditions: Male Infertility, Lead Poisoning, Testicular Diseases, Urologic and Male Genital Diseases.

Who is sponsoring clinical trial NCT00012480?

This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00012480 being conducted?

This trial has 3 study locations across California, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.