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NCT00012480 · ClinicalTrials.gov registry record
Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
A clinical trial of Male Infertility and Lead Poisoning, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- Completed
- Registry status
- 400
- Enrollment target
- 3
- Study locations
NCT00012480: Completed study of Male Infertility and Lead Poisoning, sponsored by National Institute of Environmental Health Sciences (NIEHS).
NCT00012480 is a study of Male Infertility and Lead Poisoning that has completed, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 400 participants, below the 508-participant average among 8 other Male Infertility trials with a reported enrollment target (21% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00012480, a study of Male Infertility and Lead Poisoning, has completed, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- COMPLETED
- Registry status
- 400 participants
- Enrollment target
- 3
- Study locations
Study Summary
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in men acting as semen donors in an artificial insemination program and in men representative of the general public. Our goal is to identify the mechanism(s) underlying lead's anti-fertility action.
Conditions Studied
Study Locations (3)
California
- University of Southern California Women's and Children's Hospital - Los Angeles
New York
- North Shore University Hospital - Manhasset
Pennsylvania
- Copper Hospital and Fertility Testing Laboratory and Sperm Bank - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2002-08 |
| Est. Completion | 2007-07 |
What the finished NCT00012480 record still lists
NCT00012480 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 508-participant average among 8 other Male Infertility trials with a reported enrollment target (21% lower).
The record links to 4 conditions, with Male Infertility appearing as the primary indexed condition, and to 0 interventions.
NCT00012480 reports a single indexed study location in California, New York, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00012480 about?
NCT00012480 is a clinical study titled "Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm". Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in ...
What is the current status of trial NCT00012480?
This trial is currently completed. The enrollment target is 400 participants. The study started on 2002-08. Estimated completion is 2007-07.
What conditions does trial NCT00012480 study?
This clinical trial studies the following conditions: Male Infertility, Lead Poisoning, Testicular Diseases, Urologic and Male Genital Diseases.
Who is sponsoring clinical trial NCT00012480?
This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00012480 being conducted?
This trial has 3 study locations across California, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Male Infertility
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00012480's enrollment target sits among peer trials
400 4th of 8 higher than 5 of 8 other Male Infertility trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Male Infertility trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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