Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Hypogonadism: full-pipeline trial registry
5 of 22 indexed Hypogonadism trials are currently recruiting.
Corpus placement: #756 of 28,707 conditions by registered trial count.
22 US clinical trials · 5 currently recruiting · #756 of 28,707 conditions by registered trial count
Hypogonadism: 22 US clinical trials tracked, 5 recruiting.
Hypogonadism is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Environmental Health Sciences (NIEHS), running 2 of these trials.
Enrollment posture brief
Registry condition hypogonadism
OPEN 5 | RECR 23% | LATE 7 | EARLY 9 | RANK #756 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Migraine Disorders (23% recruiting · 22 trials)
Hypogonadism lists 5 open slots (23% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypogonadism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypogonadism is recruiting below its size-band peers.
5 of 22 indexed trials (22.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypogonadism trials is spread across many organizations.
National Institute of Environmental Health Sciences (NIEHS) accounts for 2 of 22 trials (9.1%). 21 distinct sponsors appear on at least one study for this condition label.
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Most Hypogonadism trials plan to enrol fewer than 100 people.
Median target enrolment is 70 among the 22 trials that report a genuine target (sentinel values excluded). 16 of those (72.7%) plan for fewer than 100 participants.
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Hypogonadism research is mostly interventional.
17 interventional and 5 observational studies make up this index (77.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
22 total, page 1 of 1
Inherited Reproductive Disorders
National Institute of Environmental Health Sciences (NIEHS)
NCT01500447
Observation of Environment and Reproductive-Endocrine Effects
National Institute of Environmental Health Sciences (NIEHS)
NCT06280807
Adaptions and Resiliency to Multi-Stressor OpeRations
Bradley Nindl
NCT06455969
The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population
Walter Reed National Military Medical Center
NCT06247267
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
North Florida Foundation for Research and Education
NCT04460872
A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months
Tolmar
NCT06385509
Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism
VA Office of Research and Development
NCT03887936
Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone
Emory University
NCT04731376
Testosterone Replacement in Older Men and Atherosclerosis Progression
Brigham and Women's Hospital
NCT00287586
A Preliminary Clinical Study to Evaluate Fispemifene in the Treatment of Hypogonadism
QuatRx Pharmaceuticals Company
NCT00290134
The Effect of Testosterone Topical Solution (LY900011) in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel
Eli Lilly and Company
NCT01893281
Testopel ® vs. Generic Testosterone Pellets.
University of Miami
NCT04523480
Effects on the Brain of Lupron Induced Hypogonadotropic Hypogonadism With and Without Testosterone Replacement
National Institute of Mental Health (NIMH)
NCT00001412
28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men
GlaxoSmithKline
NCT00398580
Pharmacokinetics, Metabolism, Efficacy, and Safety Study of Two Testosterone Matrix Transdermal Systems
Watson Pharmaceuticals
NCT01323140
Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00470990
Testosterone and Growth Hormone for Bone Loss in Men
University of Pennsylvania
NCT00080483
Transdermal Testosterone Gel/Effect on Erection Quality as Measured by DIR
Lamm, Steven, M.D.
NCT00425568
Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure
Solvay Pharmaceuticals
NCT00998933
Efficacy Study for Use of Dutasteride (Avodart) With Testosterone Replacement
The Miriam Hospital
NCT00752869
The Effect of Various Amounts of Fat on PK of Oral Testosterone Undecanoate
Clarus Therapeutics
NCT02921386
ORAL T-6: Oral Androgens in Man-6
University of Washington
NCT00663793
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 6 |
| Phase 3 | 1 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypogonadism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypogonadism trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypogonadism page
22 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Hypogonadism trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Environmental Health Sciences (NIEHS) sponsors the most Hypogonadism trials on record, review their full trial history before evaluating a specific study. See National Institute of Environmental Health Sciences (NIEHS)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypogonadism condition card totals 22 registered trials; most-linked intervention Testosterone gel 1.62%; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.