National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

93 total trials 12 currently recruiting 71 completed

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sponsors 93 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 71 completed. 4 of these trials are in Phase 3-4 (later-stage) and 45 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Arthritis, with 4 trials.

Trial Pipeline

93 total, page 1 of 2

RECRUITING Phase 2

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

NCT05440422

RECRUITING

Natural History of Inflammatory Muscle Diseases

NCT05738824

RECRUITING

Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

NCT05567198

RECRUITING

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

NCT03510442

RECRUITING

Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease

NCT02504879

RECRUITING

Studies of Dermatologic Diseases Biospecimen Acquisition Protocol

NCT02471352

RECRUITING

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

NCT02257866

RECRUITING Phase 2

Effects of Treatments on Atopic Dermatitis

NCT01631617

RECRUITING

Natural History and Development of Spondyloarthritis

NCT01422694

RECRUITING

Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases Including Juvenile Dermatomyositis

NCT00059748

RECRUITING

Studies of the Natural History of Rheumatic Diseases

NCT00024479

RECRUITING

Study of Systemic Lupus Erythematosus

NCT00001372

ACTIVE NOT RECRUITING

Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries

NCT02281747

COMPLETED

Natural History and Pathogenesis of Alopecia in Children and Adults

NCT05502796

COMPLETED

Natural History of Coronavirus Disease (COVID-19) in Systemic Autoimmune Diseases

NCT04690816

COMPLETED Early Phase 1

Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus

NCT04233164

TERMINATED Phase 2

Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)

NCT03395340

COMPLETED Phase 1

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus

NCT02535689

COMPLETED Phase 1

Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

NCT02338999

COMPLETED Phase 1

Omalizumab for Lupus

NCT01716312

COMPLETED Phase 2

Anakinra for Inflammatory Pustular Skin Diseases

NCT01794117

COMPLETED Phase 2

Rilonacept for Deficiency of the Interleukin-1 Receptor Antagonist (DIRA)

NCT01801449

COMPLETED Phase 1

Anakinra for Behcet s Disease

NCT01441076

TERMINATED

Genetic Basis of Primary Immunodeficiencies

NCT00001788

COMPLETED

Bisphosphonate Users Radiographic Characteristics of the Hip (BURCH) Study

NCT01360099

COMPLETED Phase 2

Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis

NCT00556439

COMPLETED

Insulin Resistance and Atherosclerosis in Women With Lupus

NCT00544102

COMPLETED Phase 1

A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity

NCT00353158

COMPLETED

Progression of Spinal Fusion in Ankylosing Spondylitis

NCT00085995

COMPLETED Phase 2

Interleukin-1 Trap to Treat Autoinflammatory Diseases

NCT00094900

COMPLETED

Osteoarthritis Initiative (OAI): A Knee Health Study

NCT00080171

COMPLETED Phase 1

Electromagnetic Treatment For Bone Loss After Forearm Fracture

NCT00067834

COMPLETED NA

Protective Brace to Prevent Hand and Arm Injuries

NCT00074893

TERMINATED Phase 1

Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease

NCT00069329

COMPLETED

Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

NCT00056719

COMPLETED Phase 2

Treating Rheumatoid Arthritis With Tripterygium Wilfordi Hook F or Sulfasalazine

NCT00062465

COMPLETED

Genetic Determinants of Ankylosing Spondylitis Severity

NCT00056849

COMPLETED

Clinically Important Changes in Rheumatoid Arthritis

NCT00056602

COMPLETED Phase 2

Gabapentin in Fibromyalgia Trial (GIFT)

NCT00057278

TERMINATED Phase 2

Image Guided System for Orthopaedic Surgery

NCT00022802

COMPLETED Phase 1

Monoclonal Antibody Treatment for Systemic Lupus Erythematosus

NCT00046774

COMPLETED

Role of Antibodies in Cognitive Dysfunction in Patients With Systemic Lupus Erythematosus

NCT00042523

COMPLETED Phase 3

Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women

NCT00043719

TERMINATED Phase 1

Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients

NCT00040651

COMPLETED Phase 1

Management of Compartment Syndrome With Ultrafiltration

NCT00022815

COMPLETED Phase 2

Infliximab (Remicade ) to Treat Dermatomyositis and Polymyositis

NCT00033891

COMPLETED Phase 2

The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With Etanercept

NCT00034060

TERMINATED

Blood Component Collection From Patients With Rheumatic or Kidney Disease and Healthy Volunteers

NCT00031174

COMPLETED

Positron Emission Tomography (PET) to Locate Areas of White Blood Cell Activity

NCT00029926

TERMINATED Phase 2

Infliximab to Treat Children With Juvenile Rheumatoid Arthritis

NCT00029042

Page 1 of 2 Next →

What the Pipeline for National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Shows

According to the ClinicalTrials.gov registry, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is linked to 93 US clinical trials across every stage of research activity. Of those, 12 studies are currently recruiting, about 13% of the sponsor's indexed portfolio, and 71 are already marked complete, representing roughly 76% of the total.

The phase mix for National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 45 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is Arthritis with 4 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.