National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sits in the top decile of US sponsors by registered trial count (#253 of 15,742 sponsors by registered trial count).

93 total trials 12 currently recruiting 71 completed early-phase tilt top decile by trial count

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS): 93 sponsored US clinical trials, 12 recruiting.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sponsors 93 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 71 completed. 4 of these trials are in Phase 3-4 (later-stage) and 45 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Arthritis, with 4 trials.

Top-decile sponsor footprint

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) ranks in the top decile of sponsors by registered trial count (#253 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 62/100

71 of 80 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

93 total, page 2 of 2

COMPLETED Phase 2

Muscle Strengthening Device for Knee Osteoarthritis

NCT00007241

COMPLETED Phase 1

Effects of Exercise Poles on Older Adults During Exercise Walking

NCT00037167

COMPLETED Phase 1

Positron Emission Tomography and Magnetic Resonance Imaging to Evaluate Synovial Blood Flow in Rheumatoid Arthritis Patients

NCT00014794

COMPLETED Phase 1

Humanized LL2IGG to Treat Systemic Lupus Erythematosus

NCT00011908

COMPLETED

Registry for African Americans With Early Rheumatoid Arthritis

NCT00074555

COMPLETED

Study of Arthritis and Related Conditions

NCT00006333

COMPLETED

Scleroderma Registry

NCT00074568

COMPLETED

Consortium for the Longitudinal Evaluation of African Americans With Early Rheumatoid Arthritis (The CLEAR Registry)

NCT00815425

COMPLETED Phase 2

Infliximab for the Treatment of Early Rheumatoid Arthritis

NCT00006292

COMPLETED Phase 1

Scalp Psoriasis Treatment With a Fiber Optic Comb

NCT00007293

COMPLETED Phase 2

Etanercept for Wegener's Granulomatosis

NCT00005007

COMPLETED Phase 2

Safety and Effectiveness of h5G1.1-mAb for Dermatomyositis

NCT00005571

COMPLETED Phase 2

Oral Type I Collagen for Relieving Scleroderma

NCT00005675

COMPLETED Phase 1

Treatment of Psoriasis With Parathyroid Hormone

NCT00007306

COMPLETED Phase 3

High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide

NCT00005778

COMPLETED Phase 2

Blocking Tumor Necrosis Factor in Ankylosing Spondylitis

NCT00000433

TERMINATED Phase 3

Low-Dose Hormone Replacement Therapy and Alendronate for Osteoporosis

NCT00000430

COMPLETED Phase 2

dnaJ Peptide for Relieving Rheumatoid Arthritis

NCT00000435

COMPLETED

Genetics of Ankylosing Spondylitis

NCT00081562

COMPLETED Phase 2

BG9588 (Anti-CD40L Antibody) to Treat Lupus Nephritis

NCT00001789

COMPLETED

Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients

NCT00001679

COMPLETED

Genetics of Rheumatoid Arthritis

NCT00001678

COMPLETED Phase 2

Osteoporosis Prevention in Preadolescent Girls

NCT00000413

COMPLETED Phase 2

Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy

NCT00001677

COMPLETED

The Acquisition of Blood and Skin Samples From Normal Volunteers to Support Research Activities on Dermatologic Diseases

NCT00001505

COMPLETED Phase 1

Cyclophosphamide and Fludarabine to Treat Lupus Nephritis

NCT00001676

COMPLETED

Evaluation and Treatment of Patients With Dermatologic Diseases

NCT00001506

COMPLETED Phase 2

Tidal Lavage in Knee Osteoarthritis

NCT00000424

COMPLETED Phase 2

Methimazole to Treat Polymyositis and Dermatomyositis

NCT00001421

COMPLETED Phase 2

A Controlled Trial of Intermittent Fludarabine for Psoriatic Arthritis

NCT00001422

COMPLETED

Study of Psoriatic Arthritis

NCT00001420

COMPLETED

Juvenile Rheumatoid Arthritis Research Registry

NCT00090571

COMPLETED

National Registry for Ichthyosis and Related Disorders

NCT00074685

COMPLETED

The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis

NCT00001375

COMPLETED

Steroid Hormones, TH1/TH2 Cytokines and Reproductive Status

NCT00001376

COMPLETED Phase 3

Improving Functional Recovery After Hip Fracture

NCT00000436

COMPLETED

Genetic and Family Studies of Inherited Muscle Diseases

NCT00001331

COMPLETED

Study of Silicone-Associated Connective Tissue Diseases

NCT00001330

COMPLETED

Study and Treatment of Inflammatory Muscle Diseases

NCT00001265

COMPLETED

Genetic and Immune Studies of Rheumatoid Arthritis and Related Conditions

NCT00001291

COMPLETED NA

Isotretinoin in Preventing Skin Cancer

NCT00025012

COMPLETED Phase 2

Impact of Exercise on Older Persons With Osteoarthritis

NCT00000434

TERMINATED Phase 1

Prevention of Steroid-Induced Osteoporosis in Children

NCT00022841

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What is open in the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) pipeline

12 recruiting of 93 indexed (13% open); 71 completed (76%).

Phase mix: 4 late (III/IV) vs 45 early (I/II) (early-phase heavy).

Top condition: Arthritis (4 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS): open-pipeline peers nationwide

Peers matched on 93 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15%20%25% Total trials Recruiting share National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)National Institute on Alcohol Abuse and Alcoholism (NIAAA)Roxane LaboratoriesColorado State UniversityEndeavor HealthMcMaster UniversityTemple UniversityUniversity of PittsburghIntermountain Health Care
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 93 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) page

93 registered trials is a research-attention snapshot, not an endorsement of National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) or any single study.

  • 12 of National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Arthritis is the condition National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Arthritis trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) pipeline card: 93 registered trials from official public datasets.Report a data error.