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NCT02257866 · ClinicalTrials.gov registry record

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

A clinical trial of Giant Cell Arteritis and Takayasu's Arteritis, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

Recruiting
Registry status
4,000
Enrollment target
1
Study location

NCT02257866: Recruiting study of Giant Cell Arteritis and Takayasu's Arteritis, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

NCT02257866 is a study of Giant Cell Arteritis and Takayasu's Arteritis that is actively recruiting participants, run by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The registered enrollment target is 4,000 participants, above the 479-participant average among 7 other Giant Cell Arteritis trials with a reported enrollment target (735% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02257866, a study of Giant Cell Arteritis and Takayasu's Arteritis, is actively recruiting participants, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

RECRUITING
Registry status
4,000 participants
Enrollment target
1
Study location

Study Summary

Background: \- Vasculitis is a group of diseases that inflame and damage blood vessels and tissue. It can cause many medical problems. Few tests can diagnose the disease, and none can reliably predict a relapse. Researchers want to study people s genes and follow people over time to see how the disease affects them. Objective: \- To learn the signs, symptoms, imaging tests, genetic markers, and blood tests that can help identify people with vasculitis and predict what will happen to them over time. Eligibility: * People age 3 and older who have or are thought to have vasculitis, or are related to someone with it. * Healthy volunteers. Design: * Participants will be evaluated by a doctor who has expertise caring for patients with vasculitis. * Participants will give a blood sample. Some will give a urine sample. * Some participants may have brushings or biopsies taken from the inside lining of the nose. * Images of participants blood vessels may be taken using scans. For some scans, participants will lie on a table that moves in and out of a cylinder that takes pictures. For some scans, a contrast agent may be injected into an arm vein. Other scans may use a radioactive form of sugar. Healthy minors will not have scans. * Some participants will answer questionnaires. - Some participants will have their tests done at NIH. Others will have their doctor take the blood, saliva, or cheek swab samples and send them to NIH. * Some participants will have one visit lasting 1-2 (but sometimes up to 4) days. Some participants may have follow-up visits every 3 - 6 months, indefinitely.

Primary Outcome

To study the pathogenesis of patients affected with idiopathic systemic vasculitis, including clinical, radiographic, immunological, and genetic characteristics of the disease

Conditions Studied

Giant Cell Arteritis Takayasu's Arteritis Relapsing Polychondritis Polyarteritis Nodosa ANCA-Associated Vasculitis

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 4,000 participants
Start Date 2014-09-29
Est. Completion 2050-01-01
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

93 total trials

What NCT02257866 shows while recruiting

NCT02257866 is an observational study that tracks outcomes without assigning an intervention. Its 4,000 participants enrollment target places it among the larger protocols in the corpus, above the 479-participant average among 7 other Giant Cell Arteritis trials with a reported enrollment target (735% higher).

The record links to 5 conditions, with Giant Cell Arteritis appearing as the primary indexed condition, and to 0 interventions.

NCT02257866 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT02257866 about?

NCT02257866 is a clinical study titled "Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis". Background: \- Vasculitis is a group of diseases that inflame and damage blood vessels and tissue. It can cause many medical problems. Few tests can diagnose the disease, and none can reliably predict a relapse. Researchers want to study people s genes and follow people over time to see how the dis...

What is the current status of trial NCT02257866?

This trial is currently recruiting. The enrollment target is 4,000 participants. The study started on 2014-09-29. Estimated completion is 2050-01-01.

What conditions does trial NCT02257866 study?

This clinical trial studies the following conditions: Giant Cell Arteritis, Takayasu's Arteritis, Relapsing Polychondritis, Polyarteritis Nodosa, ANCA-Associated Vasculitis.

Who is sponsoring clinical trial NCT02257866?

This trial is sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which has 93 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02257866 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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More recruiting context for NCT02257866

Source: ClinicalTrials.gov NCT02257866, the US trial registry maintained by the National Library of Medicine. NCT02257866 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.