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NCT00056719 · ClinicalTrials.gov registry record

Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

A clinical trial of Ankylosing Spondylitis, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

Completed
Registry status
299
Enrollment target
1
Study location

NCT00056719 is a study of Ankylosing Spondylitis that has completed, run by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The registered enrollment target is 299 participants, below the 38,177-participant average among 15 other Ankylosing Spondylitis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00056719, a study of Ankylosing Spondylitis, has completed, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

COMPLETED
Registry status
299 participants
Enrollment target
1
Study location

Study Summary

This study will explore how genes may influence the severity of ankylosing spondylitis, a form of arthritis that affects the spine. Patients have inflammation of the joints of the spine, which may cause the bones of the spine to fuse, resulting in difficulty performing daily activities. Patients who developed ankylosing spondylitis after age 16 may be eligible for this study. The onset of disease is dated to the first appearance of symptoms of inflammatory low back pain or restricted spinal motion. Patients with a spondyloarthropathy other than AS may not participate. Candidates will be screened with a medical history and physical examination, blood test, and review of their medical records. They will also complete a questionnaire about their disease symptoms and medical history. Those enrolled in the study will return to the NIH Clinical Center at 6, 12, 18, 24, 30, 36, 42, 48, 54, and 60 months after screening for examination of the joints, measurement of flexibility of the spine, and a blood test. They will also complete symptoms assessment and coping questionnaires. At the first study visit (screening visit), x-rays will be taken of the pelvis, lower back, and neck, if recent X-rays (within 1 year) are not available. These x-ray studies will be repeated on all patients every two years during the study (at 24 and 48 months after screening).

Conditions Studied

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 299 participants
Start Date 2003-06-19

What the Registry Record Tells You About NCT00056719

The ClinicalTrials.gov registry entry for NCT00056719 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 299 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 38,177-participant average among 15 other Ankylosing Spondylitis trials with a reported enrollment target (99% lower). The listed sponsor is National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which has 93 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Ankylosing Spondylitis appearing as the primary indexed condition, and to 0 interventions.

NCT00056719 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00056719 about?

NCT00056719 is a clinical study titled "Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study". This study will explore how genes may influence the severity of ankylosing spondylitis, a form of arthritis that affects the spine. Patients have inflammation of the joints of the spine, which may cause the bones of the spine to fuse, resulting in difficulty performing daily activities. Patients wh...

What is the current status of trial NCT00056719?

This trial is currently completed. The enrollment target is 299 participants. The study started on 2003-06-19.

What conditions does trial NCT00056719 study?

This clinical trial studies the following conditions: Ankylosing Spondylitis.

Who is sponsoring clinical trial NCT00056719?

This trial is sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which has 93 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00056719 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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