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ClinicalTrials.gov 7 recruiting now official registry

Ankylosing Spondylitis clinical trials

7 of 16 indexed Ankylosing Spondylitis trials are currently recruiting.

16 US clinical trials · 7 currently recruiting

Ankylosing Spondylitis is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), running 2 of these trials.

The research picture

Ankylosing Spondylitis has 16 registered US clinical trials, 7 of them open to new participants right now, about 44% of the total.

7
recruiting participants now
44%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Phase 11Phase 21Phase 32Phase 41

Active & Recent Trials

16 total, page 1 of 1

RECRUITING 20,000 participants

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

NCT05635266

RECRUITING 20,000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Exactech

NCT05603728

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING 500 participants

Rheumatology Diet Study

University of Central Florida

NCT06339957

RECRUITING 300 participants

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

TScan Therapeutics

NCT06587828

RECRUITING 125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

NCT04751396

ACTIVE NOT RECRUITING 521,292 participants

Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT02281747

ACTIVE NOT RECRUITING 925 participants

OTIS Cimzia Pregnancy Registry

University of California, San Diego

NCT01797224

ACTIVE NOT RECRUITING Phase 3 508 participants

A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

UCB Biopharma SRL

NCT04436640

ACTIVE NOT RECRUITING NA 101 participants

Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity

Brigham and Women's Hospital

NCT05715463

COMPLETED Phase 3 859 participants

Effect of Secukinumab on Radiographic Progression in Ankylosing Spondylitis as Compared to GP2017 (Adalimumab Biosimilar)

Novartis Pharmaceuticals

NCT03259074

COMPLETED Phase 4 322 participants

Study Estimating the Clinical Difference Between 300 mg and 150 mg of Secukinumab Following Dose Escalation to 300 mg in Patients With Ankylosing Spondylitis

Novartis Pharmaceuticals

NCT03350815

COMPLETED 299 participants

Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00056719

COMPLETED Phase 2 208 participants

Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis

Pfizer

NCT01786668

COMPLETED Phase 1 17 participants

A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers

UCB Biosciences

NCT02154425

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ankylosing Spondylitis Trial Landscape

16 indexed Ankylosing Spondylitis studies · 7 recruiting (44%).

Phase mix: 3 late (III/IV) vs 2 early (I/II).

Top sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (2 trials), 9 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ankylosing Spondylitis?

PlainTrial tracks 16 US clinical trials for Ankylosing Spondylitis, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ankylosing Spondylitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.