Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 7 recruiting now full pipeline small index

Ankylosing Spondylitis: full-pipeline trial registry

7 of 16 indexed Ankylosing Spondylitis trials are currently recruiting.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 7 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Ankylosing Spondylitis: 16 US clinical trials tracked, 7 recruiting.

Ankylosing Spondylitis is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), running 2 of these trials.

Enrollment posture brief

Registry condition ankylosing-spondylitis

OPEN 7 | RECR 44% | LATE 3 | EARLY 2 | RANK #1060 | SPON 2

Nearest open-share peer: Acute Respiratory Distress Syndrome (44% recruiting · 32 trials)

Adolescent62.5%Alcohol Intoxication56.3%Ankylosing Spondylitis (this)44%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Ankylosing Spondylitis

Ankylosing Spondylitis lists 7 open slots (44% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ankylosing Spondylitis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ankylosing Spondylitis is recruiting below its size-band peers.

    7 of 16 indexed trials (43.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ankylosing Spondylitis trials is spread across many organizations.

    National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) accounts for 2 of 16 trials (12.5%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ankylosing Spondylitis enrolment sits around 508 participants.

    Median target enrolment is 508 among the 16 trials that report a genuine target (sentinel values excluded). 1 of those (6.3%) plan for fewer than 100 participants.

  4. Ankylosing Spondylitis research leans observational.

    6 interventional and 10 observational studies make up this index (37.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 32Phase 41

Open and recent trials

16 total, page 1 of 1

RECRUITING 20,000 participants

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

NCT05635266

RECRUITING 20,000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Exactech

NCT05603728

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING 500 participants

Rheumatology Diet Study

University of Central Florida

NCT06339957

RECRUITING 300 participants

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

TScan Therapeutics

NCT06587828

RECRUITING 125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

NCT04751396

ACTIVE NOT RECRUITING 521,292 participants

Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT02281747

ACTIVE NOT RECRUITING 925 participants

OTIS Cimzia Pregnancy Registry

University of California, San Diego

NCT01797224

ACTIVE NOT RECRUITING Phase 3 508 participants

A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

UCB Biopharma SRL

NCT04436640

ACTIVE NOT RECRUITING NA 101 participants

Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity

Brigham and Women's Hospital

NCT05715463

COMPLETED Phase 3 859 participants

Effect of Secukinumab on Radiographic Progression in Ankylosing Spondylitis as Compared to GP2017 (Adalimumab Biosimilar)

Novartis Pharmaceuticals

NCT03259074

COMPLETED Phase 4 322 participants

Study Estimating the Clinical Difference Between 300 mg and 150 mg of Secukinumab Following Dose Escalation to 300 mg in Patients With Ankylosing Spondylitis

Novartis Pharmaceuticals

NCT03350815

COMPLETED 299 participants

Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00056719

COMPLETED Phase 2 208 participants

Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis

Pfizer

NCT01786668

COMPLETED Phase 1 17 participants

A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers

UCB Biosciences

NCT02154425

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 2
Phase 4 1

Named interventions

Most-linked intervention names on Ankylosing Spondylitis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

AIN457 150 mg Biological
1 trials
GP2017 (adalimumab biosimilar) Biological
1 trials
Tofacitinib 10 mg Drug
1 trials
Tofacitinib 5 mg Drug
1 trials
Tofacitinib 2 mg Drug
1 trials
Certolizumab Pegol Biological
1 trials
Breast milk sampling Procedure
1 trials
300 mg double-blinded secukinumab Drug
1 trials

US sites by state

Facility locations filed on Ankylosing Spondylitis trials. A trial with sites in several states counts in each.

California 8 trials
Florida 6 trials
Maryland 5 trials
Texas 4 trials
Pennsylvania 4 trials
Ohio 4 trials
North Carolina 4 trials
Oregon 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ankylosing Spondylitis page

16 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ankylosing Spondylitis condition card totals 16 registered trials; most-linked intervention AIN457 150 mg; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.