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Arthritis, Rheumatoid clinical trials
5 of 29 indexed Arthritis, Rheumatoid trials are currently recruiting.
29 US clinical trials · 5 currently recruiting
Arthritis, Rheumatoid is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 7 of these trials.
The research picture
Arthritis, Rheumatoid has 29 registered US clinical trials, 5 of them open to new participants right now, about 17% of the total.
- 5
- recruiting participants now
- 17%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 7
- top sponsor: Pfizer
Active & Recent Trials
29 total, page 1 of 1
IMPACT - AndHealth Autoimmune Research Registry
AndHealth
NCT05883371
A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)
Merck Sharp & Dohme
NCT07176390
Chronic Pain in Rheumatoid Arthritis
Northwestern University
NCT05038553
Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
University of Michigan
NCT00748254
R-2487 in Patients With Rheumatoid Arthritis
Rise Therapeutics
NCT05961592
INFINITY™ With ADAPTIS™ Technology Study
Stryker Trauma and Extremities
NCT04594993
Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis
Pfizer
NCT02092467
COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis
GlaxoSmithKline
NCT00113308
A Multi-Center Trial to Compare Three Doses of Meloxicam and Placebo in Patients With Rheumatoid Arthritis
Boehringer Ingelheim
NCT00042068
Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty Study
DePuy Orthopaedics
NCT00289133
A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications
Pfizer
NCT00856544
BI 695501 Compared to Adalimumab in Patients With Active Rheumatoid Arthritis
Boehringer Ingelheim
NCT02137226
A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis
Pfizer
NCT00814307
Comparison Of 6 CP-690,550 Doses Vs.Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis
Pfizer
NCT00413660
The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00001375
Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis
Amgen
NCT02114931
Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)
Janssen Biotech
NCT01004432
Long-term Assessment of Safety and Efficacy of BI 695501 in Patients With Rheumatoid Arthritis
Boehringer Ingelheim
NCT02640612
A Study To Compare The Effectiveness Of Tofacitinib 11 Mg Once A Day To Tofacitinib 5 Mg Twice A Day
Pfizer
NCT04267380
Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00001679
Real-world Clinical Efficacy of Abatacept in the T3 Data Registry
Arthritis Northwest P
NCT01555879
Long-Term Safety Follow-Up Of Subjects Previously Enrolled In Rheumatoid Arthritis Studies Of CP-690,550
Pfizer
NCT00414661
A Safety and Pharmacokinetics Study in Participants With Rheumatoid Arthritis
Eli Lilly and Company
NCT00380744
Stepping Up For Inflammatory Arthritis
University of Pennsylvania
NCT02912221
Evaluating Safety of Escalating Doses of Tilmanocept by IV Injection and SPECT Imaging in Subjects With and Without RA
Navidea Biopharmaceuticals
NCT02865434
Low Dose Naltrexone for Chronic Pain From Arthritis
VA Office of Research and Development
NCT03008590
A Study To Evaluate The Safety And Pharmacokinetic Profile Of A P38 Inhibitor (PH-797804) In Subjects With Rheumatoid Arthritis Who Are Also Taking Methotrexate
Pfizer
NCT00620685
6-Month Phase I/II Open Label PRTX-100 in Previous Rheumatoid Arthritis Study Participants and Sera Collection
Protalex
NCT02330445
Study To Evaluate The Pharmacokinetic Interaction Between PLA-695 And Methotrexate In Adults With Rheumatoid Arthritis
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00440492
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 4 |
| Phase 3 | 8 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Arthritis, Rheumatoid Trial Landscape
29 indexed Arthritis, Rheumatoid studies · 5 recruiting (17%).
Phase mix: 9 late (III/IV) vs 9 early (I/II).
Top sponsor: Pfizer (7 trials), 9 others listed. 29 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Arthritis, Rheumatoid?
PlainTrial tracks 29 US clinical trials for Arthritis, Rheumatoid, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Arthritis, Rheumatoid?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.