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2026 data Public-data reference. official source

Arthritis, Rheumatoid

Open-data reference.

28 US clinical trials · 5 currently recruiting

Active & Recent Trials

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING Phase 2 182 participants

A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)

Merck Sharp & Dohme

NCT07176390

RECRUITING 125 participants

Chronic Pain in Rheumatoid Arthritis

Northwestern University

NCT05038553

RECRUITING 113 participants

Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis

University of Michigan

NCT00748254

RECRUITING Phase 1 73 participants

R-2487 in Patients With Rheumatoid Arthritis

Rise Therapeutics

NCT05961592

ACTIVE NOT RECRUITING 200 participants

INFINITY™ With ADAPTIS™ Technology Study

Stryker Trauma and Extremities

NCT04594993

COMPLETED Phase 4 4,372 participants

Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis

Pfizer

NCT02092467

COMPLETED Phase 3 2,208 participants

COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis

GlaxoSmithKline

NCT00113308

COMPLETED Phase 3 1,000 participants

A Multi-Center Trial to Compare Three Doses of Meloxicam and Placebo in Patients With Rheumatoid Arthritis

Boehringer Ingelheim

NCT00042068

COMPLETED NA 938 participants

Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty Study

DePuy Orthopaedics

NCT00289133

COMPLETED Phase 3 795 participants

A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications

Pfizer

NCT00856544

COMPLETED Phase 3 645 participants

BI 695501 Compared to Adalimumab in Patients With Active Rheumatoid Arthritis

Boehringer Ingelheim

NCT02137226

COMPLETED Phase 3 611 participants

A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis

Pfizer

NCT00814307

COMPLETED Phase 2 509 participants

Comparison Of 6 CP-690,550 Doses Vs.Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis

Pfizer

NCT00413660

COMPLETED 500 participants

The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001375

COMPLETED Phase 3 467 participants

Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis

Amgen

NCT02114931

COMPLETED Phase 3 433 participants

Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Janssen Biotech

NCT01004432

COMPLETED Phase 3 430 participants

Long-term Assessment of Safety and Efficacy of BI 695501 in Patients With Rheumatoid Arthritis

Boehringer Ingelheim

NCT02640612

COMPLETED 250 participants

Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001679

COMPLETED 200 participants

Real-world Clinical Efficacy of Abatacept in the T3 Data Registry

Arthritis Northwest P

NCT01555879

COMPLETED 162 participants

Long-Term Safety Follow-Up Of Subjects Previously Enrolled In Rheumatoid Arthritis Studies Of CP-690,550

Pfizer

NCT00414661

COMPLETED Phase 1 121 participants

A Safety and Pharmacokinetics Study in Participants With Rheumatoid Arthritis

Eli Lilly and Company

NCT00380744

COMPLETED NA 71 participants

Stepping Up For Inflammatory Arthritis

University of Pennsylvania

NCT02912221

COMPLETED Phase 1 39 participants

Evaluating Safety of Escalating Doses of Tilmanocept by IV Injection and SPECT Imaging in Subjects With and Without RA

Navidea Biopharmaceuticals

NCT02865434

COMPLETED Phase 2 29 participants

Low Dose Naltrexone for Chronic Pain From Arthritis

VA Office of Research and Development

NCT03008590

COMPLETED Phase 2 27 participants

A Study To Evaluate The Safety And Pharmacokinetic Profile Of A P38 Inhibitor (PH-797804) In Subjects With Rheumatoid Arthritis Who Are Also Taking Methotrexate

Pfizer

NCT00620685

COMPLETED Phase 1 13 participants

6-Month Phase I/II Open Label PRTX-100 in Previous Rheumatoid Arthritis Study Participants and Sera Collection

Protalex

NCT02330445

COMPLETED Phase 1

Study To Evaluate The Pharmacokinetic Interaction Between PLA-695 And Methotrexate In Adults With Rheumatoid Arthritis

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00440492

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 4
Phase 3 8
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Arthritis, Rheumatoid Trial Landscape

ClinicalTrials.gov lists 28 US studies indexed under Arthritis, Rheumatoid, and 5 of those are currently open to recruitment — roughly 18% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Arthritis, Rheumatoid shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Arthritis, Rheumatoid is led by Pfizer with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Arthritis, Rheumatoid?

PlainTrial tracks 28 US clinical trials for Arthritis, Rheumatoid, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Arthritis, Rheumatoid?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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