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ClinicalTrials.gov 5 recruiting now full pipeline

Arthritis, Rheumatoid: full-pipeline trial registry

5 of 29 indexed Arthritis, Rheumatoid trials are currently recruiting.

Corpus placement: #552 of 28,707 conditions by registered trial count.

29 US clinical trials · 5 currently recruiting · #552 of 28,707 conditions by registered trial count

Arthritis, Rheumatoid: 29 US clinical trials tracked, 5 recruiting.

Arthritis, Rheumatoid is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 7 of these trials.

Enrollment posture brief

Registry condition arthritis-rheumatoid

OPEN 5 | RECR 17% | LATE 9 | EARLY 9 | RANK #552 | SPON 7

Nearest open-share peer: Influenza (17% recruiting · 157 trials)

Advanced Breast Cancer62.1%Amyloidosis51.7%Burnout, Professional24.1%Arthritis, Rheumatoid (this)17%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Arthritis, Rheumatoid

Arthritis, Rheumatoid lists 5 open slots (17% of 29 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Arthritis, Rheumatoid on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Arthritis, Rheumatoid is recruiting below its size-band peers.

    5 of 29 indexed trials (17.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Arthritis, Rheumatoid research.

    Pfizer accounts for 7 of 29 trials (24.1%). 20 distinct sponsors appear on at least one study for this condition label.

  3. Typical Arthritis, Rheumatoid enrolment sits around 298 participants.

    Median target enrolment is 298 among the 28 trials that report a genuine target (sentinel values excluded). 6 of those (21.4%) plan for fewer than 100 participants.

  4. Arthritis, Rheumatoid splits between interventional and observational designs.

    20 interventional and 9 observational studies make up this index (69% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 24Phase 38Phase 41

Open and recent trials

29 total, page 1 of 1

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING Phase 2 182 participants

A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)

Merck Sharp & Dohme

NCT07176390

RECRUITING 125 participants

Chronic Pain in Rheumatoid Arthritis

Northwestern University

NCT05038553

RECRUITING 113 participants

Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis

University of Michigan

NCT00748254

RECRUITING Phase 1 73 participants

R-2487 in Patients With Rheumatoid Arthritis

Rise Therapeutics

NCT05961592

ACTIVE NOT RECRUITING 200 participants

INFINITY™ With ADAPTIS™ Technology Study

Stryker Trauma and Extremities

NCT04594993

COMPLETED Phase 4 4,372 participants

Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis

Pfizer

NCT02092467

COMPLETED Phase 3 2,208 participants

COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis

GlaxoSmithKline

NCT00113308

COMPLETED Phase 3 1,000 participants

A Multi-Center Trial to Compare Three Doses of Meloxicam and Placebo in Patients With Rheumatoid Arthritis

Boehringer Ingelheim

NCT00042068

COMPLETED NA 938 participants

Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty Study

DePuy Orthopaedics

NCT00289133

COMPLETED Phase 3 795 participants

A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications

Pfizer

NCT00856544

COMPLETED Phase 3 645 participants

BI 695501 Compared to Adalimumab in Patients With Active Rheumatoid Arthritis

Boehringer Ingelheim

NCT02137226

COMPLETED Phase 3 611 participants

A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis

Pfizer

NCT00814307

COMPLETED Phase 2 509 participants

Comparison Of 6 CP-690,550 Doses Vs.Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis

Pfizer

NCT00413660

COMPLETED 500 participants

The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001375

COMPLETED Phase 3 467 participants

Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis

Amgen

NCT02114931

COMPLETED Phase 3 433 participants

Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Janssen Biotech

NCT01004432

COMPLETED Phase 3 430 participants

Long-term Assessment of Safety and Efficacy of BI 695501 in Patients With Rheumatoid Arthritis

Boehringer Ingelheim

NCT02640612

COMPLETED 298 participants

A Study To Compare The Effectiveness Of Tofacitinib 11 Mg Once A Day To Tofacitinib 5 Mg Twice A Day

Pfizer

NCT04267380

COMPLETED 250 participants

Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001679

COMPLETED 200 participants

Real-world Clinical Efficacy of Abatacept in the T3 Data Registry

Arthritis Northwest P

NCT01555879

COMPLETED 162 participants

Long-Term Safety Follow-Up Of Subjects Previously Enrolled In Rheumatoid Arthritis Studies Of CP-690,550

Pfizer

NCT00414661

COMPLETED Phase 1 121 participants

A Safety and Pharmacokinetics Study in Participants With Rheumatoid Arthritis

Eli Lilly and Company

NCT00380744

COMPLETED NA 71 participants

Stepping Up For Inflammatory Arthritis

University of Pennsylvania

NCT02912221

COMPLETED Phase 1 39 participants

Evaluating Safety of Escalating Doses of Tilmanocept by IV Injection and SPECT Imaging in Subjects With and Without RA

Navidea Biopharmaceuticals

NCT02865434

COMPLETED Phase 2 29 participants

Low Dose Naltrexone for Chronic Pain From Arthritis

VA Office of Research and Development

NCT03008590

COMPLETED Phase 2 27 participants

A Study To Evaluate The Safety And Pharmacokinetic Profile Of A P38 Inhibitor (PH-797804) In Subjects With Rheumatoid Arthritis Who Are Also Taking Methotrexate

Pfizer

NCT00620685

COMPLETED Phase 1 13 participants

6-Month Phase I/II Open Label PRTX-100 in Previous Rheumatoid Arthritis Study Participants and Sera Collection

Protalex

NCT02330445

COMPLETED Phase 1

Study To Evaluate The Pharmacokinetic Interaction Between PLA-695 And Methotrexate In Adults With Rheumatoid Arthritis

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00440492

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 4
Phase 3 8
Phase 4 1

Named interventions

Most-linked intervention names on Arthritis, Rheumatoid records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
CP-690,550 Drug
4 trials
BI 695501 Drug
2 trials
US-licensed Humira® Drug
1 trials
ABP 501 Biological
1 trials
Whole body planar SPECT imaging (60 Minutes post-injection) Procedure
1 trials
Whole body planar SPECT imaging (15 Minutes post-injection) Procedure
1 trials
SPECT Imaging (180 Minutes post-injection) Procedure
1 trials

US sites by state

Facility locations filed on Arthritis, Rheumatoid trials. A trial with sites in several states counts in each.

California 16 trials
Florida 14 trials
Arizona 14 trials
Colorado 10 trials
Alabama 9 trials
New York 8 trials
Illinois 8 trials
Maryland 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Arthritis, Rheumatoid page

29 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Arthritis, Rheumatoid trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Pfizer sponsors the most Arthritis, Rheumatoid trials on record, review their full trial history before evaluating a specific study. See Pfizer's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Arthritis, Rheumatoid condition card totals 29 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.