National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.
Trial Pipeline
2,006 total, page 6 of 41
A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.
NCT04840199
COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial)
NCT05289037
Phase I Norovirus Challenge Model
NCT04174560
A Phase 1 Trial to Evaluate CAP256V2LS in Healthy Adults
NCT04408963
Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age
NCT04520659
Community Dynamics of Malaria Transmission in Humans and Mosquitoes at Maferinyah Sub-Prefecture, Guinea
NCT04969913
Evaluation of Two Zika Viruses for Use in Controlled Human Infection Models (CHIM)
NCT05123222
Blood-Stage Plasmodium Vivax Cell Bank
NCT05095272
An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge
NCT05048875
COVID Protection After Transplant-Immunosuppression Reduction
NCT05077254
Empagliflozin as a Treatment for Severe Congenital Neutropenia Due to G6PC3 Deficiency
NCT05078879
A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants
NCT05184452
Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplex®)
NCT05099965
Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination
NCT04722003
Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)
NCT04918147
Natural History of Systemic and Nasal Mucosal Immunity After Influenza Vaccination in a Pediatric Population
NCT04963166
PF-07304814 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
NCT05780541
Trial to Evaluate L9LS in Healthy Adults
NCT05019729
Assess the Safety and Immunogenicity of One or Two Doses of Sing2016 M2SR H3N2 Influenza Vaccine
NCT04960397
The Safety of Administering a Second Dose of a COVID-19 mRNA Vaccine in Individuals Who Experienced a Systemic Allergic Reaction to an Initial Dose
NCT04977479
Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum
NCT04518228
Vaccination for Recovered Inpatients With COVID-19 (VATICO)
NCT04969250
Influenza Challenge Study to Determine the Optimal Infection Dose and Safety of a Recombinant H3N2 (A/Texas/71/2017 (H3N2, Clade 3C3a) Influenza Strain
NCT04978454
COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders
NCT05000216
COVID-19 Protection After Transplant Pilot Study
NCT04969263
ACTIV-5 / Big Effect Trial (BET-C) for the Treatment of COVID-19
NCT04988035
SARS-CoV-2 Immune Responses After COVID-19 Therapy and Subsequent Vaccine
NCT04952402
Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease
NCT03983837
MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
NCT05780463
Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) After Receipt of EUA Vaccines
NCT04889209
First-in-Human Clinical Trial of a Mosaic Quadrivalent Influenza Vaccine Compared With a Licensed Inactivated Seasonal QIV in Healthy Adults
NCT04896086
DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia
NCT04775953
Liver Transplantation With Tregs at UCSF
NCT03654040
Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)
NCT06729593
COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and Dysregulations
NCT04852276
ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19
NCT04843761
Aviptadil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)
NCT06729606
SARS-COV2 Pandemic Serosurvey in a Rare Disease Population
NCT04609085
COVID-19 and Anti-CD14 Treatment Trial
NCT04391309
COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations
NCT04761822
PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US
NCT04582266
Safety and Immunogenicity Study of a SARS-CoV-2 (COVID-19) Variant Vaccine (mRNA-1273.351) in Naïve and Previously Vaccinated Adults
NCT04785144
Chimpanzee Adenovirus and Self-Amplifying mRNA Prime-Boost Prophylactic Vaccines Against SARS-CoV-2 in Healthy Adults
NCT04776317
A Study of SARS CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 Vaccine
NCT04811664
Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals
NCT04272242
Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)
NCT04216589
AZD7442 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
NCT05780437
Mepolizumab in Episodic Angioedema With Eosinophilia
NCT04128371
VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
NCT05780281
BRII-196/BRII-198 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
NCT05780424
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 858 |
| Phase 2 | 433 |
| Phase 3 | 123 |
| Phase 4 | 54 |
Therapeutic Areas
What the Pipeline for National Institute of Allergy and Infectious Diseases (NIAID) Shows
According to the ClinicalTrials.gov registry, National Institute of Allergy and Infectious Diseases (NIAID) is linked to 2,006 US clinical trials across every stage of research activity. Of those, 155 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 1,642 are already marked complete, representing roughly 82% of the total.
The phase mix for National Institute of Allergy and Infectious Diseases (NIAID) reports 177 late-stage studies (Phase 3 and Phase 4 combined) and 1,291 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Allergy and Infectious Diseases (NIAID) is HIV Infections with 195 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.