National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.
Trial Pipeline
2,006 total, page 7 of 41
B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B
NCT04193189
Evaluation of AMG 714 for Vitiligo
NCT04338581
Adaptive COVID-19 Treatment Trial 4 (ACTT-4)
NCT04640168
COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C
NCT04588363
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects
NCT04408950
Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult Participants
NCT04212091
A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin
NCT03891901
ACTIV-5 / Big Effect Trial (BET-B) for the Treatment of COVID-19
NCT04583969
ACTIV-5 / Big Effect Trial (BET-A) for the Treatment of COVID-19
NCT04583956
Phase 1 Study of SAR440894 vs Placebo
NCT04441905
Dose, Safety, Tolerability and Immunogenicity of an Influenza H10 Stabilized Stem Ferritin Vaccine, VRC-FLUNPF0103-00-VP, in Healthy Adults
NCT04579250
Safety and Pharmacokinetics of VT-1598
NCT04208321
The Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less Than 12 Years of Age
NCT03760458
SARS-COV2 Pandemic Serosurvey and Blood Sampling
NCT04334954
ACTIV-2: A Study for Outpatients With COVID-19
NCT04518410
Adaptive COVID-19 Treatment Trial 3 (ACTT-3)
NCT04492475
LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
NCT05780268
ACTIV-3: Therapeutics for Inpatients With COVID-19
NCT04501978
Surveillance of Individuals Following SARS-CoV-2 Infection
NCT04383444
Collection of Anti-SARS-CoV-2 Immune Plasma
NCT04344977
COVID-19 Associated Lymphopenia Pathogenesis Study in Blood
NCT04401436
Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19
NCT04358068
Adaptive COVID-19 Treatment Trial 2 (ACTT-2)
NCT04401579
COVID-19: Human Epidemiology and Response to SARS-CoV-2
NCT04375761
Immunophenotyping Assessment in a COVID-19 Cohort
NCT04378777
Safety and Immunogenicity Study of 2019-nCoV Vaccine (mRNA-1273) for Prophylaxis of SARS-CoV-2 Infection (COVID-19)
NCT04283461
Adaptive COVID-19 Treatment Trial (ACTT)
NCT04280705
Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males
NCT04692077
Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected Adults
NCT04177355
Trial to Evaluate CIS43LS in Healthy Adults
NCT04206332
Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1
NCT03739996
Safety and Pharmacokinetic Study of Tenofovir Alafenamide (TAF)/Elvitegravir (EVG) Administered Rectally
NCT04047420
Treg Modulation With CD28 and IL-6 Receptor Antagonists
NCT04066114
Safety and Pharmacokinetics of Rezafungin
NCT04117607
H1N1v Virus Challenge Study in Healthy Subjects
NCT04044352
Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine
NCT04025580
Dosage-Escalation Study of the Safety and Immunogenicity of a Novel Rabies Vaccine ChAd155-RG vs. the Comparator RABAVERT Vaccine in Healthy Adult Subjects
NCT04019444
Suppression Of Bacterial Vaginosis (BV) [SUBVert]
NCT03930745
Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants
NCT03934541
Asymptomatic Congenital CMV Treatment
NCT03301415
Safety and Immunotherapeutic Activity of an Anti-PD-1 Antibody (Cemiplimab) in Participants With HIV-1 on Suppressive cART
NCT03787095
Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants
NCT03881696
Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult Participants
NCT03928821
A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With Aztreonam
NCT03978091
Evaluating the Safety and Immunogenicity of AGS-v PLUS, a Universal Mosquito-Borne Disease and Mosquito Control Vaccine
NCT04009824
Intravenous Fosfomycin Pharmacokinetics Study
NCT03910673
Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age
NCT03916185
Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in People With Indolent Systemic Mastocytosis
NCT03770273
Flublok or Fluzone With Advax-CpG55.2 or AF03
NCT03945825
A Clinical Trial in Healthy, HIV-1-Uninfected Adult Participants to Compare the Safety, Tolerability and Immunogenicity of CH505TF gp120 Produced From Stably Transfected Cells to CH505TF gp120 Produced From Transiently Transfected Cells
NCT03856996
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 858 |
| Phase 2 | 433 |
| Phase 3 | 123 |
| Phase 4 | 54 |
Therapeutic Areas
What the Pipeline for National Institute of Allergy and Infectious Diseases (NIAID) Shows
According to the ClinicalTrials.gov registry, National Institute of Allergy and Infectious Diseases (NIAID) is linked to 2,006 US clinical trials across every stage of research activity. Of those, 155 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 1,642 are already marked complete, representing roughly 82% of the total.
The phase mix for National Institute of Allergy and Infectious Diseases (NIAID) reports 177 late-stage studies (Phase 3 and Phase 4 combined) and 1,291 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Allergy and Infectious Diseases (NIAID) is HIV Infections with 195 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.