National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials 155 currently recruiting 1642 completed

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Trial Pipeline

2,006 total, page 5 of 41

NOT YET RECRUITING Phase 2

Small Trial of Alendronate Impact on the Reservoir of HIV

NCT07216794

NOT YET RECRUITING Phase 1

A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies

NCT07569029

NOT YET RECRUITING

Study of Oral Food Challenge Biomarkers (SAFER)

NCT07279467

NOT YET RECRUITING Phase 4

Steroid Treatment for Severe Acute Respiratory Infection (STAR) Trial

NCT07199192

COMPLETED Phase 1

Phase 1 Study on Bioavailability, Food Effect, and Drug-Drug Interaction of ALG-097558 Tablets in Healthy Volunteers

NCT06945276

COMPLETED Phase 1

Study of a Human Bispecific Antibody VRC-HIVMAB0121-00-AB (CAP256J3LS) Administered Intravenously or Subcutaneously to Healthy Adults

NCT06585891

COMPLETED Phase 1

Evaluation of the Protective Efficacy of TV003 or Previous Zika Infection Against Infection With ZIKV-SJRP Challenge Compared to DENV and ZIKV-naïve Controls Against Infection With ZIKV-SJRP Challenge

NCT06805487

COMPLETED Phase 1

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

NCT06441968

COMPLETED Phase 1

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

NCT06444048

COMPLETED Phase 1

Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function

NCT03896750

TERMINATED Phase 1

Safety Study of SLV213 for the Treatment of COVID-19.

NCT06146374

COMPLETED Phase 4

A Study of Doxycycline to Treat Chlamydial Infection

NCT05840159

COMPLETED Phase 2

Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy

NCT06005610

COMPLETED Phase 1

Low Pathogenicity Avian H10N7 Influenza Virus in a Healthy Human Challenge Model

NCT05436444

COMPLETED Phase 1

To Investigate Safety, Reactogenicity and Immunogenicity of VIR-1388 Compared With Placebo in Participants Without HIV

NCT05854381

COMPLETED Phase 1

Phase I Safety Study of B/HPIV3/S-6P Vaccine Via Nasal Spray in Adults

NCT06026514

COMPLETED Phase 1

Effect of Bismuth Subsalicylate on the Gut Microbiome and Host Response in Healthy Adults

NCT05930197

COMPLETED Phase 1

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Mosaic Hexavalent Influenza Vaccine VRC-FLUMOS0116-00-VP (FluMos-v2) in Healthy Adults

NCT05968989

COMPLETED Phase 1

Neonatal Phase 1 Valacyclovir Study

NCT05468619

COMPLETED Phase 1

Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults

NCT05913973

TERMINATED Phase 2

CD40L Antagonism in Rheumatoid Arthritis (RA)

NCT05306353

TERMINATED Phase 2

Transcutaneous Cervical Vagus Nerve Stimulation (tcVNS) in JIA

NCT05710640

COMPLETED Phase 1

Safety of Intravenous Apramycin in Adults

NCT05590728

COMPLETED Phase 2

A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV

NCT05630885

TERMINATED Phase 1

Siplizumab in T1DM

NCT05574335

COMPLETED

Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products

NCT02242968

COMPLETED Phase 1

Safety Study of Intravenous Ertapenem in Combination With Zidebactam (WCK 6777)

NCT05645757

COMPLETED Phase 1

Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding NP-GT8 and IL-12, With or Without a TLR-agonist-Adjuvanted HIV Env Trimer 4571 Boost, in Adults Without HIV

NCT05781542

COMPLETED Phase 1

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

NCT05755620

COMPLETED Phase 1

A Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding a Native-like HIV Env Trimer and Interleukin-12 (INO-6160), Alone or in a Prime-boost Regimen With 3M-052-AF + Alum Adjuvanted VRC HIV Env Trimer 4571 in Adult Participants Without HIV

NCT05828095

COMPLETED Phase 2

A Phase 2 Randomized Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for Mpox

NCT05740982

COMPLETED Phase 2

COVID Protection After Transplant - Sanofi GSK (CPAT-SG) Study

NCT05518487

COMPLETED Phase 1

A Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRCHIVMAB0115-00-AB (VRC01.23LS), Administered Intravenously or Subcutaneously to Healthy Adults

NCT05627258

COMPLETED Phase 1

Evaluating the Safety and Immunogenicity of Stabilized CH505 TF chTrimer in Healthy, HIV-uninfected Adult Participants.

NCT04915768

TERMINATED Phase 2

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

NCT05306873

COMPLETED Phase 4

Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis

NCT05436535

COMPLETED Phase 2

Phase 2 Shigella Vaccine and Challenge

NCT04242264

COMPLETED Phase 1

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

NCT05406583

COMPLETED Phase 1

A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa

NCT05453578

COMPLETED Phase 1

Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus

NCT05048238

COMPLETED Phase 1

Safety and Immunogenicity of CJCV2 With and Without ALFQ

NCT05500417

COMPLETED Phase 2

Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine

NCT05512949

TERMINATED Phase 3

Study of Tecovirimat for Human Mpox Virus

NCT05534984

COMPLETED Phase 1

A Clinical Trial to Evaluate Safety, Tolerability, and Immunogenicity of Adjuvanted HIV-1 Fusion Peptide Conjugate Vaccine Alone or in Prime-Boost Regimens With Adjuvanted HIV-1 Envelope Trimer 4571 and HIV-1 Trimer 6931 Vaccines in Healthy Adults

NCT05470400

COMPLETED Phase 1

Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications

NCT05104723

TERMINATED Phase 1

Targeted Investigation of Microbiome Elimination

NCT05177328

COMPLETED Phase 1

Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults

NCT05398796

COMPLETED Phase 1

Safety and Immunogenicity of BPL-1357, A BPL-Inactivated, Whole-Virus, Universal Influenza Vaccine

NCT05027932

COMPLETED Phase 1

Anthrax AV7909 Liquid vs Lyophilized

NCT04660201

COMPLETED Phase 1

Safety, Tolerability, and Immunogenicity Study of Sm-p80 + GLA-SE (SchistoShield(R)) Vaccine in Healthy Adults

NCT05292391

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What the Pipeline for National Institute of Allergy and Infectious Diseases (NIAID) Shows

According to the ClinicalTrials.gov registry, National Institute of Allergy and Infectious Diseases (NIAID) is linked to 2,006 US clinical trials across every stage of research activity. Of those, 155 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 1,642 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Allergy and Infectious Diseases (NIAID) reports 177 late-stage studies (Phase 3 and Phase 4 combined) and 1,291 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Allergy and Infectious Diseases (NIAID) is HIV Infections with 195 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.