BioXcel Therapeutics

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, BioXcel Therapeutics sits in the top decile of US sponsors by registered trial count (#1,049 of 15,742 sponsors by registered trial count).

13 total trials 1 currently recruiting 9 completed top decile by trial count

BioXcel Therapeutics: 13 sponsored US clinical trials, 1 recruiting.

BioXcel Therapeutics sponsors 13 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 9 completed. 6 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Schizoaffective Disorder, with 2 trials.

Top-decile sponsor footprint

BioXcel Therapeutics ranks in the top decile of sponsors by registered trial count (#1,049 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

9 of 11 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 1

Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

NCT05025605

ACTIVE NOT RECRUITING Phase 2

Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar Disorder

NCT07116694

COMPLETED Phase 4

Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder

NCT06041646

TERMINATED Phase 3

Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)

NCT05665088

COMPLETED Phase 3

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)

NCT05658510

COMPLETED Phase 3

Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)

NCT05271552

TERMINATED Phase 2

An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia

NCT05276830

COMPLETED Phase 1

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal

NCT04470050

COMPLETED Phase 3

Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder

NCT04276883

COMPLETED Phase 3

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia

NCT04268303

COMPLETED Phase 1

Sub-Lingual Dexmedetomidine in Agitation Associated With Dementia

NCT04251910

COMPLETED Phase 1

Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia

NCT04010305

COMPLETED Phase 1

A Trial of BXCL701 and Pembrolizumab in Patients With mCRPC Either Small Cell Neuroendocrine Prostate Cancer or Adenocarcinoma Phenotype.

NCT03910660

What is open in the BioXcel Therapeutics pipeline

1 recruiting of 13 indexed (8% open); 9 completed (69%).

Phase mix: 6 late (III/IV) vs 7 early (I/II) (balanced across stages).

Top condition: Schizoaffective Disorder (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

BioXcel Therapeutics: open-pipeline peers nationwide

Peers matched on 13 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

BioXcel Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 12.912.91313.1 0%2%4%6%8%10% Total trials Recruiting share BioXcel TherapeuticsAdaptimmuneAgennixAkili Interactive LabsAlumisAndrei IagaruCorporal Michael J. Crescenz VA Medical CenterFresenius Medical Care North AmericaLG Chem
BioXcel Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

BioXcel Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 13 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this BioXcel Therapeutics page

13 registered trials is a research-attention snapshot, not an endorsement of BioXcel Therapeutics or any single study.

  • 1 of BioXcel Therapeutics's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Schizoaffective Disorder is the condition BioXcel Therapeutics studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Schizoaffective Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

BioXcel Therapeutics pipeline card: 13 registered trials from official public datasets.Report a data error.