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NCT04843761 · ClinicalTrials.gov registry record · Phase 3

ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19

A Phase 3 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 3
Development phase
473
Enrollment target

NCT04843761 is a Phase 3 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 473 participants.

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The verdict

NCT04843761, a Phase 3 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 3
Development phase
473 participants
Enrollment target

Study Summary

This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with either a study drug plus current standard of care (SOC), or with placebo plus current SOC. Substudy H1: Aviptadil for Severely Ill Inpatients With COVID-19 (NCT06729606) Substudy H2: Remdesivir for Severely Ill Inpatients With COVID-19 (NCT06729593)

Interventions

  • DRUG Corticosteroid
  • BIOLOGICAL Remdesivir
  • DRUG Remdesivir Placebo
  • BIOLOGICAL Aviptadil
  • DRUG Aviptadil Placebo

Trial Details

FieldValue
Enrollment Target 473 participants
Start Date 2021-04-20
Est. Completion 2022-11-20
Phase Phase 3

What the Registry Record Tells You About NCT04843761

The ClinicalTrials.gov registry entry for NCT04843761 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 473 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Corticosteroid is the first listed.

NCT04843761 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04843761 about?

NCT04843761 is a clinical study titled "ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19". This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with either a study drug plus current standard of care (SOC), or with pla...

What is the current status of trial NCT04843761?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 473 participants. The study started on 2021-04-20. Estimated completion is 2022-11-20.

What interventions are being tested in trial NCT04843761?

The interventions under investigation include: Corticosteroid (DRUG), Remdesivir (BIOLOGICAL), Remdesivir Placebo (DRUG), Aviptadil (BIOLOGICAL), Aviptadil Placebo (DRUG).

Who is sponsoring clinical trial NCT04843761?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.