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NCT04391309 · ClinicalTrials.gov registry record · Phase 2

COVID-19 and Anti-CD14 Treatment Trial

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Terminated
Registry status
Phase 2
Development phase
49
Enrollment target

NCT04391309 is a Phase 2 study that was terminated before completion, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 49 participants.

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The verdict

NCT04391309, a Phase 2 study, was terminated before completion, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

TERMINATED
Registry status
Phase 2
Development phase
49 participants
Enrollment target

Study Summary

This study aims to address the following objectives: 1. To determine the efficacy of IC14, an anti-CD14 chimeric monoclonal antibody, in patients hospitalized with respiratory disease and hypoxemia due to SARS-CoV-2, in terms of improving the time to resolution of disease. 2. To determine the efficacy of IC14 in reducing the severity of respiratory disease in patients hospitalized with respiratory disease due to SARS-CoV-2. 3. To determine the safety of IC14 in patients hospitalized with respiratory disease due to SARS-CoV-2.

Interventions

  • OTHER Placebo
  • DRUG remdesivir
  • BIOLOGICAL anti-CD14

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2021-04-12
Est. Completion 2022-02-04
Phase Phase 2

What the Registry Record Tells You About NCT04391309

The ClinicalTrials.gov registry entry for NCT04391309 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT04391309 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04391309 about?

NCT04391309 is a clinical study titled "COVID-19 and Anti-CD14 Treatment Trial". This study aims to address the following objectives: 1. To determine the efficacy of IC14, an anti-CD14 chimeric monoclonal antibody, in patients hospitalized with respiratory disease and hypoxemia due to SARS-CoV-2, in terms of improving the time to resolution of disease. 2. To determine the effic...

What is the current status of trial NCT04391309?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 49 participants. The study started on 2021-04-12. Estimated completion is 2022-02-04.

What interventions are being tested in trial NCT04391309?

The interventions under investigation include: Placebo (OTHER), remdesivir (DRUG), anti-CD14 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04391309?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.