National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 18 of 41

COMPLETED

Immune Response to Varicella-Zoster Vaccination and Infection

NCT00921999

COMPLETED Phase 2

Influenza Vaccine in Pregnant Women

NCT00905125

COMPLETED

Viral Triggers in Pediatric Lung Transplantation

NCT00891865

TERMINATED Phase 2

A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis

NCT00913692

COMPLETED Phase 2

High Dose IMVAMUNE® in Vaccinia-Naive Individuals

NCT00879762

TERMINATED

Host Factors in Invasive and Recurrent Staphylococcus Aureus Infection

NCT00911430

COMPLETED Phase 1

Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation

NCT00768729

TERMINATED Phase 2

Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female (MTF) Transgender Persons Who Have Sex With Men

NCT00865566

TERMINATED Phase 2

Combination Pain Therapy in HIV Neuropathy

NCT00863057

COMPLETED Phase 2

Live Zoster Vaccine in HIV-Infected Adults on Antiretroviral Therapy

NCT00851786

COMPLETED Phase 2

A Randomized, Double-Blind, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis

NCT00890162

COMPLETED Phase 1

Phase I Study of the Safety and Immunogenicity of BSAM-2/Alhydrogel +CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria in Adults in the US and Mali

NCT00889616

COMPLETED Phase 1

Dose Escalation Study of SQ109 in Healthy Adult Volunteers

NCT00866190

COMPLETED Phase 2

Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus

NCT00730028

COMPLETED Phase 2

Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"

NCT00729937

COMPLETED

Normal Blood, Bone Marrow and Buccal Mucosa Protocol

NCT00806364

COMPLETED Phase 1

VRC 307: A Double-Blind, Randomized Phase I Study of the Safety and Immunogenicity of a Prime-Boost Schedule of the Investigational DNA Trivalent Influenza Vaccine, VRC-FLUDNA047-00-VP, Followed by the 2008/2009 Seasonal Influenza Trivalent Inactivat...

NCT00858611

COMPLETED

Estivation of Malaria Vector Mosquitoes in the Sahelian Region of Mali

NCT00863408

COMPLETED Phase 1

Malaria Challenge With NF54 Strain

NCT00744133

COMPLETED Phase 4

Anti-TNF Agents for the Treatment of Rheumatoid Arthritis

NCT00837434

COMPLETED Phase 1

Safety and Immune Response to a Recombinant Adenovirus HIV-1 Vaccine in Healthy Adults

NCT00695877

COMPLETED Phase 1

Safety of Acidform Lubricant in HIV-Uninfected Women

NCT00850837

COMPLETED Phase 1

Safety and Immune Response to Preventive HIV Immunization With Adenovirus Serotype 5 or 35 Vector

NCT00801697

COMPLETED

The Underlying Mechanisms For S. Aureus Infection And Colonization Of Skin in People With Atopic Dermatitis With And Without Eczema Herpeticum (MRSA)

NCT00822276

TERMINATED Phase 1

Interleukin-7 (CYT107) Treatment of Idiopathic CD4 Lymphocytopenia: Expansion of CD4 T Cells (ICICLE)

NCT00839436

COMPLETED Phase 1

Pertussis Vaccine in Healthy Pregnant Women

NCT00707148

COMPLETED Phase 2

Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults

NCT00820846

COMPLETED Phase 1

Biomarker-based Cockroach Sublingual Immunotherapy Study (BioCSI)

NCT00829985

COMPLETED Phase 1

Safety and Immune Response to Two Doses of rDEN2/4delta30 Dengue Vaccine

NCT00920517

COMPLETED Phase 1

BCG Vaccination Delivered Intradermally, Orally and by Combined Routes

NCT00396370

COMPLETED Phase 1

Safety of and Immune Response to a Dengue Virus Vaccine (rDEN3-3'Ddelta30) in Healthy Adults

NCT00712803

COMPLETED Phase 2

Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection

NCT00801632

COMPLETED Phase 2

Analysis of Response of Subjects With Atopic Dermatitis or Psoriasis to Oral Vitamin D3

NCT00789880

COMPLETED

Blood Markers of Inflammation, Blood Clotting and Blood Vessel Function in HIV-infected Adults

NCT00776412

COMPLETED Phase 1

Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults

NCT00574600

COMPLETED Phase 1

H5N1 (Clade 2) Vaccination of Adults and Elderly

NCT00680069

COMPLETED Phase 2

Abatacept and Cyclophosphamide Combination Therapy for Lupus Nephritis

NCT00774852

COMPLETED Phase 2

Vitamin D3 in Systemic Lupus Erythematosus

NCT00710021

TERMINATED Phase 4

Switching Anti-TNF-Alpha Agents in Rheumatoid Arthritis (RA)

NCT00796705

COMPLETED Phase 1

Vaccine for Prevention of Bird Flu

NCT00776711

COMPLETED Phase 2

LEA29Y (Belatacept) Emory Edmonton Protocol

NCT00468403

COMPLETED Phase 1

Safety of and Immune Response to Recombinant Live-Attenuated Influenza H6N1 Virus Vaccine Vaccine

NCT00734175

COMPLETED Phase 2

H5N1 Priming and Boosting Strategies

NCT00703053

COMPLETED Phase 1

Safety, Reactogenicity and Immunogenicity of MVA in Hematopoietic Stem Cell Transplant (HSCT) Subjects

NCT00565929

COMPLETED Phase 2

Study of Milk Allergy and Tolerance in Children

NCT00778258

COMPLETED Phase 1

Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis

NCT00723489

TERMINATED Phase 4

Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C Infections

NCT00742326

COMPLETED Phase 3

Bacterial Vaginosis Home Screening to Prevent STDs

NCT00667368

COMPLETED Phase 1

Phase I Study of HIV Adenoviral Vector Vaccine in Healthy Subjects Using Needle or Biojector Injection

NCT00709605

COMPLETED Phase 1

Safety and Immunogenicity of Peru-15-pCTB in Healthy Adult Subjects

NCT00654108

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.