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NCT00574600 · ClinicalTrials.gov registry record · Phase 1

Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults

A Phase 1 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
48
Enrollment target
4
Study locations

NCT00574600 is a Phase 1 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 48 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (89% lower). The trial reports 4 study locations across 3 states.

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The verdict

NCT00574600, a Phase 1 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
48 participants
Enrollment target
4
Study locations

Study Summary

The purpose of this study is to evaluate the safety of and immune response to an experimental DNA HIV vaccine followed by boosting with an experimental modified vaccinia HIV vaccine (MVA) in HIV uninfected adults.

Conditions Studied

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL SAAVI DNA-C2 vaccine
  • BIOLOGICAL SAAVI MVA-C vaccine

Study Locations (4)

Massachusetts

  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS) - Boston
  • Fenway Health (FH) CRS - Boston

Gauteng

  • Soweto HVTN CRS - Johannesburg

Western Cape

  • Emavundleni CRS - Cape Town

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2008-11
Est. Completion 2013-01
Phase Phase 1

What the Registry Record Tells You About NCT00574600

The ClinicalTrials.gov registry entry for NCT00574600 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (89% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT00574600 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Massachusetts, Gauteng, Western Cape.

Frequently Asked Questions

What is clinical trial NCT00574600 about?

NCT00574600 is a clinical study titled "Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults". The purpose of this study is to evaluate the safety of and immune response to an experimental DNA HIV vaccine followed by boosting with an experimental modified vaccinia HIV vaccine (MVA) in HIV uninfected adults.

What is the current status of trial NCT00574600?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2008-11. Estimated completion is 2013-01.

What conditions does trial NCT00574600 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00574600?

The interventions under investigation include: Placebo (BIOLOGICAL), SAAVI DNA-C2 vaccine (BIOLOGICAL), SAAVI MVA-C vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00574600?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00574600 being conducted?

This trial has 4 study locations across Massachusetts, Gauteng, Western Cape. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.