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NCT00905125 · ClinicalTrials.gov registry record · Phase 2

Influenza Vaccine in Pregnant Women

A Phase 2 study of Influenza, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
102
Enrollment target
9
Study locations

NCT00905125 is a Phase 2 study of Influenza that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 102 participants, below the 36,803-participant average among 156 other Influenza trials with a reported enrollment target (100% lower). The trial reports 9 study locations across 9 states.

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The verdict

NCT00905125, a Phase 2 study of Influenza, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
102 participants
Enrollment target
9
Study locations

Study Summary

In pregnant women, flu may cause complications like pneumonia (infection of the lungs) or hospitalization. In the United States (US) it is recommend that all women get flu vaccine if they are going to be pregnant or deliver during the flu season but only a few studies have measured a pregnant woman's immune response (the body's defense against the flu) after getting the flu vaccine. About 200, 18-39 year old, inclusive, pregnant women in their second or third trimester (from 14 weeks of gestation to term, inclusive) will be enrolled in this US based study. Participation will be about 8 months in duration. Women will be randomized (assigned by chance) to receive either Fluzone® or Fluarix®. Blood collection will occur on Day 0 and 28 days post vaccination.

Conditions Studied

Interventions

  • BIOLOGICAL Fluzone®
  • BIOLOGICAL Fluarix®

Study Locations (9)

Georgia

  • Emory University School of Medicine - Gynecology and Obstetrics - Atlanta

Iowa

  • University of Iowa - Iowa City

Maryland

  • University of Maryland Baltimore - Baltimore

Minnesota

  • Mayo Clinic, Rochester - Vaccine Research Group - Rochester

Missouri

  • Saint Louis University - St Louis

North Carolina

  • Duke University Medical Center - Durham

Tennessee

  • Vanderbilt University - Nashville

Texas

  • Baylor College of Medicine - Molecular Virology and Microbiology - Houston

Trial Details

FieldValue
Enrollment Target 102 participants
Start Date 2009-06
Est. Completion 2010-03
Phase Phase 2

What the Registry Record Tells You About NCT00905125

The ClinicalTrials.gov registry entry for NCT00905125 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 102 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 36,803-participant average among 156 other Influenza trials with a reported enrollment target (100% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Influenza appearing as the primary indexed condition, and to 2 interventions - of which Fluzone® is the first listed.

NCT00905125 reports 9 study locations spanning 9 distinct geographic areas - top geographies include Georgia, Iowa, Maryland.

Frequently Asked Questions

What is clinical trial NCT00905125 about?

NCT00905125 is a clinical study titled "Influenza Vaccine in Pregnant Women". In pregnant women, flu may cause complications like pneumonia (infection of the lungs) or hospitalization. In the United States (US) it is recommend that all women get flu vaccine if they are going to be pregnant or deliver during the flu season but only a few studies have measured a pregnant woman'...

What is the current status of trial NCT00905125?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 102 participants. The study started on 2009-06. Estimated completion is 2010-03.

What conditions does trial NCT00905125 study?

This clinical trial studies the following conditions: Influenza.

What interventions are being tested in trial NCT00905125?

The interventions under investigation include: Fluzone® (BIOLOGICAL), Fluarix® (BIOLOGICAL).

Who is sponsoring clinical trial NCT00905125?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00905125 being conducted?

This trial has 9 study locations across Georgia, Iowa, Maryland, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.