National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 19 of 41

COMPLETED Phase 2

Adherence and Acceptability to and Blood Levels of Tenofovir Gel and Tablets in HIV Uninfected Women

NCT00592124

COMPLETED Phase 3

Short-Term vs. Long-Term Valganciclovir Therapy for Symptomatic Congenital CMV Infections

NCT00466817

COMPLETED

Genomics of Chronic Renal Allograft Rejection (The GoCAR Study)

NCT00611702

COMPLETED

Intensive Viral Dynamics Substudy of A5248

NCT00852618

COMPLETED Phase 1

Study of Viral Load Decay Rates in HIV Infected Participants Starting Treatment With Raltegravir (RAL) and Emtricitabine/Tenofovir Disoproxil Fumarate (TDF)

NCT00660972

COMPLETED Phase 1

Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study

NCT00646152

COMPLETED Phase 1

Safety, Reactogenicity, and Immunogenicity of Inactivated Influenza A/H7/N7 Vaccine in Healthy Adults

NCT00546585

COMPLETED Phase 1

Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4delta30) in Healthy Adults

NCT00537147

COMPLETED Phase 1

Safety of and Immune Response to Recombinant Live-Attenuated Parainfluenza Type 1 Virus Vaccine

NCT00641017

COMPLETED Phase 2

Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women

NCT00604175

COMPLETED Phase 2

H9 Priming Study in Healthy Adults

NCT00617331

COMPLETED Phase 1

Safety of and Immune Response to an Adenoviral HIV-1 Vaccine in Healthy Adults

NCT00618605

TERMINATED Phase 1

Enteroaggregative E.Coli (EAEC)

NCT00362869

TERMINATED Phase 2

Etanercept for the Treatment of Lupus Nephritis

NCT00447265

COMPLETED Phase 1

Ebola and Marburg Virus Vaccines

NCT00605514

COMPLETED

Dyskinesia, Heterotaxy and Congenital Heart Disease

NCT00608556

COMPLETED

Influenza in People With Normal and Weakened Immune Systems

NCT00533182

COMPLETED NA

HIV Screening in the Emergency Department Setting

NCT00667186

COMPLETED Phase 3

Optimizing Treatment for Treatment-Experienced, HIV-Infected People

NCT00537394

COMPLETED NA

MRI to Measure Liver Fat Content

NCT00594412

COMPLETED Phase 1

A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial

NCT00580606

COMPLETED Phase 1

Responses to Immunization With Keyhole Limpet Hemocyanin Administered by Scarification and the Intradermal Route

NCT00614731

TERMINATED Phase 2

Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis

NCT00302952

COMPLETED Phase 2

Effect of Addition of Raltegravir (MK-0518) to PI- or NNRTI-Based ART Regimens in HIV Infected Subjects With Undetectable Viral Load

NCT00515827

COMPLETED

Live Lung Donor Retrospective Study

NCT00553397

COMPLETED Phase 1

Safety and Effectiveness of PENNVAX-B Vaccine Alone, With Il-12, or IL-15 in Healthy Adults

NCT00528489

COMPLETED Phase 1

Safety and Pharmacokinetics (PK) of Raltegravir in HIV (Human Immunodeficiency Virus)-Infected Children and Adolescents

NCT00485264

COMPLETED NA

Study of Provider Computer Alerts Designed to Improve Delivery of HIV Care

NCT00678600

COMPLETED Phase 1

Single Group Study of the Safety of and Immune Response to a Bird Flu Vaccine (H7N3) in Healthy Adults

NCT00516035

COMPLETED

Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival

NCT00531921

TERMINATED Phase 2

Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome

NCT00527878

COMPLETED

Collection of Samples and Data for the National Marrow Donor Program Repository

NCT00495300

COMPLETED Phase 1

Determining Responses to Two Different Vaccines in HIV and HCV Infected Individuals

NCT00393276

COMPLETED

Live Kidney Donor Study

NCT00608283

COMPLETED Phase 1

Safety of and Immune Response to a DNA HIV Vaccine Followed By Boosting With One of Two Serotypes of Adenoviral Vector HIV Vaccine in Healthy Adults

NCT00472719

COMPLETED Phase 1

Proleukin and Rapamune in Type 1 Diabetes

NCT00525889

TERMINATED Phase 2

Study of Antithymocyte Globulin for Treatment of New-onset T1DM

NCT00515099

COMPLETED

Malaria Incidence in Infants in Bancoumana, Mali

NCT00508417

COMPLETED Phase 1

Expanded Characterization of Immune Response to Merck Adenovirus 5 Gag/Pol/Nef Vaccine Given to HIV Uninfected Adults

NCT00486408

COMPLETED Phase 1

Phase I Open-Label Study of Recombinant DNA Plasmid Vaccine, VRC-AVIDNA036-00-VP, Encoding for Influenza Virus H5 Hemagglutinin Protein Given Intradermally

NCT00489931

COMPLETED Phase 1

An Open Label Non-Randomized Dose Escalating Trial to Assess Safety and Tolerability of Alb-Interferon Alfa 2b Every Two Weeks With Ribavirin Among HIV/HCV Coinfected Individuals

NCT00489385

COMPLETED Phase 1

Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth

NCT00459316

COMPLETED Phase 1

Pneumococcal Reference Standard

NCT00479323

COMPLETED

Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients

NCT00466804

COMPLETED Phase 3

Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men

NCT00458393

COMPLETED Phase 1

Single Group Study of the Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults

NCT00488046

TERMINATED Phase 1

Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1

NCT00490100

COMPLETED Phase 1

Phase 1 Safety Study of Two Experimental HIV Vaccines

NCT00479999

COMPLETED

Pilot Study of Genotypic Analysis

NCT00421837

COMPLETED Phase 2

Oral Immunotherapy for Childhood Egg Allergy

NCT00461097

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.