Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00820846 · ClinicalTrials.gov registry record · Phase 2

Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
299
Enrollment target

NCT00820846: Completed Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00820846 is a Phase 2 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 299 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (125% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00820846, a Phase 2 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
299 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety of and immune response to a two-vaccine regimen in healthy, HIV-uninfected adults who have never received an HIV preventive vaccine before.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL pGA2/JS7 DNA vaccine
  • BIOLOGICAL MVA/HIV62 vaccine

Trial Details

FieldValue
Enrollment Target 299 participants
Start Date 2009-01
Est. Completion 2014-09
Phase Phase 2

What the finished NCT00820846 record still lists

NCT00820846 is an interventional study that assigns participants to a tested intervention. The registered 299 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (125% higher).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00820846 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00820846 about?

NCT00820846 is a clinical study titled "Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults". The purpose of this study is to evaluate the safety of and immune response to a two-vaccine regimen in healthy, HIV-uninfected adults who have never received an HIV preventive vaccine before.

What is the current status of trial NCT00820846?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 299 participants. The study started on 2009-01. Estimated completion is 2014-09.

What interventions are being tested in trial NCT00820846?

The interventions under investigation include: Placebo (BIOLOGICAL), pGA2/JS7 DNA vaccine (BIOLOGICAL), MVA/HIV62 vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00820846?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00820846's enrollment target sits among peer trials

299 188th of 2000 higher than 1,813 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00353483 · 300 participants

    Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells

  • NCT00588185 · 300 participants · NA

    [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

  • NCT00682032 · 300 participants · NA

    The Effect of Beta-glucan in Non-Small Cell Lung Cancer

  • NCT00870064 · 300 participants · NA

    The Treatment of Type I Open Fractures in Pediatrics

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00820846, the US trial registry maintained by the National Library of Medicine. NCT00820846 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.