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NCT00723489 · ClinicalTrials.gov registry record · Phase 1

Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis

A Phase 1 study of Atopic Dermatitis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
82
Enrollment target
3
Study locations

NCT00723489 is a Phase 1 study of Atopic Dermatitis that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 82 participants, below the 609-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (87% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT00723489, a Phase 1 study of Atopic Dermatitis, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
82 participants
Enrollment target
3
Study locations

Study Summary

The main objective of the Atopic Dermatitis and Vaccinia Immunization Network (ADVN) is to reduce the risk of the fatal reaction, eczema vaccinatum (EV), to the smallpox vaccination in those with atopic dermatitis (AD). Since vaccination with live vaccinia virus (VV) in individuals with AD increases the risk of EV, a yellow fever vaccine was chosen. The purpose of this study is to determine the immune response to a yellow fever vaccine in adults with AD.

Conditions Studied

Interventions

  • BIOLOGICAL Live Yellow Fever Vaccine (YFV-17D)
  • DRUG YFV-17D Placebo

Study Locations (3)

California

  • University of California, San Diego - San Diego

Colorado

  • National Jewish Health - Denver

Oregon

  • Oregon Health & Science University - Portland

Trial Details

FieldValue
Enrollment Target 82 participants
Start Date 2008-08
Est. Completion 2011-04
Phase Phase 1

What the Registry Record Tells You About NCT00723489

The ClinicalTrials.gov registry entry for NCT00723489 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 609-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (87% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which Live Yellow Fever Vaccine (YFV-17D) is the first listed.

NCT00723489 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Colorado, Oregon.

Frequently Asked Questions

What is clinical trial NCT00723489 about?

NCT00723489 is a clinical study titled "Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis". The main objective of the Atopic Dermatitis and Vaccinia Immunization Network (ADVN) is to reduce the risk of the fatal reaction, eczema vaccinatum (EV), to the smallpox vaccination in those with atopic dermatitis (AD). Since vaccination with live vaccinia virus (VV) in individuals with AD increases...

What is the current status of trial NCT00723489?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 82 participants. The study started on 2008-08. Estimated completion is 2011-04.

What conditions does trial NCT00723489 study?

This clinical trial studies the following conditions: Atopic Dermatitis.

What interventions are being tested in trial NCT00723489?

The interventions under investigation include: Live Yellow Fever Vaccine (YFV-17D) (BIOLOGICAL), YFV-17D Placebo (DRUG).

Who is sponsoring clinical trial NCT00723489?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00723489 being conducted?

This trial has 3 study locations across California, Colorado, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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