National Eye Institute (NEI)
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, National Eye Institute (NEI) sits in the top decile of US sponsors by registered trial count (#145 of 15,742 sponsors by registered trial count).
National Eye Institute (NEI): 221 sponsored US clinical trials, 18 recruiting.
National Eye Institute (NEI) sponsors 221 registered US clinical trials on ClinicalTrials.gov, 18 of them currently recruiting, and 179 completed. 11 of these trials are in Phase 3-4 (later-stage) and 86 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Age-related Macular Degeneration, with 8 trials.
Top-decile sponsor footprint
National Eye Institute (NEI) ranks in the top decile of sponsors by registered trial count (#145 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
179 of 196 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
221 total, page 5 of 5
Normal Human Electro-Oculogram
NCT00001610
Studies of Families With Hereditary Cataracts
NCT00001609
Anti-tac Therapy FOR Uveitis
NCT00001526
Intravenous Immunoglobulin Therapy in Optic Neuritis
NCT00000117
The Effects of Light Reduction on Retinopathy of Prematurity (Light-ROP)
NCT00000156
Long Term Follow-Up of Diabetic Retinopathy
NCT00001395
Study of Usher Syndromes, Type 1 and Type 2
NCT00001347
Diabetic Retinopathy and Visual Function Study
NCT00001346
Herpetic Eye Disease Study (HEDS) II
NCT00000139
Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients
NCT00001311
Tissue Studies of Human Eye Diseases
NCT00001310
Study of Eye Tissue for Sarcoidosis
NCT00001278
Analysis of Eye Tissue
NCT00001224
Cysteamine Eye Drops to Treat Corneal Crystals in Cystinosis
NCT00001213
Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity
NCT00000133
Visual Stimulus and Eye Movement
NCT00001172
Gyrate Atrophy of the Choroid and Retina
NCT00001166
Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens
NCT00001161
Pigment Dispersion Syndrome With and Without Glaucoma
NCT00001152
Visual Function and Ocular Pigmentation in Albinism
NCT00001153
The Contact Lens and Myopia Progression (CLAMP) Study
NCT00009529
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 62 |
| Phase 2 | 24 |
| Phase 3 | 11 |
Therapeutic Areas
What is open in the National Eye Institute (NEI) pipeline
18 recruiting of 221 indexed (8% open); 179 completed (81%).
Phase mix: 11 late (III/IV) vs 86 early (I/II) (early-phase heavy).
Top condition: Age-related Macular Degeneration (8 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
National Eye Institute (NEI): open-pipeline peers nationwide
Peers matched on 221 registered trials and 8% open enrollment, not the therapeutic-area sidebar.
National Eye Institute (NEI) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 221 trials (± recruiting share)
- Otsuka Pharmaceutical Development & Commercialization · 221 trials · 4% recruiting
- Florida State University · 219 trials · 21% recruiting
- Penn State University · 219 trials · 17% recruiting
- University of Louisville · 217 trials · 21% recruiting
Sponsors near 8% open enrollment (± trial volume)
- GE Healthcare · 8% recruiting · 99 trials
- HealthPartners Institute · 8% recruiting · 146 trials
- Oregon Research Institute · 8% recruiting · 62 trials
- Arcutis Biotherapeutics · 8% recruiting · 25 trials
Related
What to do with this National Eye Institute (NEI) page
221 registered trials is a research-attention snapshot, not an endorsement of National Eye Institute (NEI) or any single study.
- 18 of National Eye Institute (NEI)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Age-related Macular Degeneration is the condition National Eye Institute (NEI) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Age-related Macular Degeneration trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Eye Institute (NEI) pipeline card: 221 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.