Arcutis Biotherapeutics

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Arcutis Biotherapeutics sits in the top decile of US sponsors by registered trial count (#626 of 15,742 sponsors by registered trial count).

25 total trials 2 currently recruiting 22 completed early-phase tilt top decile by trial count

Arcutis Biotherapeutics: 25 sponsored US clinical trials, 2 recruiting.

Arcutis Biotherapeutics sponsors 25 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 22 completed. 9 of these trials are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Seborrheic Dermatitis, with 1 trials.

Top-decile sponsor footprint

Arcutis Biotherapeutics ranks in the top decile of sponsors by registered trial count (#626 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 79/100

22 of 23 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (95.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

25 total, page 1 of 1

RECRUITING Phase 1

Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

NCT07453602

RECRUITING Phase 1

Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis

NCT07340216

COMPLETED Phase 2

Safety Study of Roflumilast Cream 0.05% in Infants Aged 3 Months to Less Than 2 Years With Atopic Dermatitis

NCT06998056

COMPLETED Phase 3

Topical Roflumilast to Treat Scalp and Body Psoriasis (ARRECTOR)

NCT05028582

COMPLETED Phase 3

Trial of PDE4 Inhibition With Roflumilast (ARQ-154) Foam 0.3% for the Management of Seborrheic Dermatitis (STRATUM)

NCT04973228

COMPLETED Phase 3

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)

NCT04845620

TERMINATED Phase 2

Safety and Efficacy of ARQ-252 Cream 0.3% in Subjects With Non-Segmental Facial Vitiligo

NCT04811131

COMPLETED Phase 2

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-216)

NCT04746911

COMPLETED Phase 3

Open Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis

NCT04804605

COMPLETED Phase 3

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-II)

NCT04773600

COMPLETED Phase 3

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis

NCT04773587

COMPLETED Phase 2

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-215)

NCT04655313

COMPLETED Phase 2

Long-Term Safety of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

NCT04445987

COMPLETED Phase 1

Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema

NCT04378569

COMPLETED Phase 1

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Adolescents and Adults With Chronic Plaque Psoriasis

NCT04279119

COMPLETED Phase 3

Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis

NCT04286607

COMPLETED Phase 2

Safety and Efficacy of ARQ-154 Foam in Adolescent and Adult Subjects With Scalp and Body Psoriasis

NCT04128007

COMPLETED Phase 1

Pharmacokinetics (PK), Safety, Efficacy and Maximal Use PK of ARQ-151 in Adolescents/Children With Mild/Moderate Eczema

NCT04156191

COMPLETED Phase 3

Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis

NCT04211363

COMPLETED Phase 3

Twin Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis

NCT04211389

COMPLETED Phase 2

Safety and Efficacy of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

NCT04091646

COMPLETED Phase 2

Safety and Efficacy of ARQ-151 Cream in Adolescents and Adults With Atopic Dermatitis

NCT03916081

COMPLETED Phase 2

Long-Term Safety of ARQ-151 Cream in Adult Subjects With Chronic Plaque Psoriasis

NCT03764475

COMPLETED Phase 2

The Safety, Efficacy and Pharmacokinetics of ARQ-151 Cream in Subjects With Chronic Plaque Psoriasis

NCT03638258

COMPLETED Phase 1

Safety, Pharmacokinetics and Efficacy of ARQ-151 Cream in Adults With Mild to Moderate Chronic Plaque Psoriasis

NCT03392168

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 10
Phase 3 9

What is open in the Arcutis Biotherapeutics pipeline

2 recruiting of 25 indexed (8% open); 22 completed (88%).

Phase mix: 9 late (III/IV) vs 16 early (I/II) (early-phase heavy).

Top condition: Seborrheic Dermatitis (1 trial), 4 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Arcutis Biotherapeutics: open-pipeline peers nationwide

Peers matched on 25 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

Arcutis Biotherapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share Arcutis BiotherapeuticsArcus BiosciencesArdelyxDrexel University College of MedicineFisher and Paykel HealthcareMedtronic EndovascularNovartis PharmaceuticalsPenumbraSK Life Science
Arcutis Biotherapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Arcutis Biotherapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 25 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this Arcutis Biotherapeutics page

25 registered trials is a research-attention snapshot, not an endorsement of Arcutis Biotherapeutics or any single study.

  • 2 of Arcutis Biotherapeutics's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Seborrheic Dermatitis is the condition Arcutis Biotherapeutics studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Seborrheic Dermatitis trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Arcutis Biotherapeutics pipeline card: 25 registered trials from official public datasets.Report a data error.