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Retinitis Pigmentosa
Open-data reference.
38 US clinical trials · 15 currently recruiting
Active & Recent Trials
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
Jaeb Center for Health Research
NCT05589714
Cell Collection to Study Eye Diseases
National Eye Institute (NEI)
NCT01432847
High Resolution Retinal Imaging
University of Pennsylvania
NCT01866371
Stem Cell Ophthalmology Treatment Study II
MD Stem Cells
NCT03011541
Rod and Cone Mediated Function in Retinal Disease
National Eye Institute (NEI)
NCT02617966
Retinal Imaging in Patients With Inherited Retinal Degenerations
University of California, San Francis
NCT00254605
Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration
Ray Therapeutics
NCT06375239
Adaptive Optics Imaging of Outer Retinal Diseases
Food and Drug Administration (FDA)
NCT05355415
Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)
jCyte
NCT06912633
Study of BEST1 Vitelliform Macular Dystrophy
Columbia University
NCT05809635
Promising ROd-cone DYstrophy Gene therapY
SparingVision
NCT05748873
BS01 in Patients With Retinitis Pigmentosa
Bionic Sight
NCT04278131
Experimental and Clinical Studies of Retinal Stimulation
University of Michigan
NCT03635645
The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
University of Rochester
NCT06319872
A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa
Sumitomo Pharma America
NCT06891885
Oral N-acetylcysteine for Retinitis Pigmentosa
Johns Hopkins University
NCT05537220
A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa
Ocugen
NCT06388200
Rate of Progression in EYS Related Retinal Degeneration
Jaeb Center for Health Research
NCT04127006
Prospective Natural History Study of Retinitis Pigmentosa
SparingVision
NCT04285398
Natural History of PRPF31 Mutation-Associated Retinal Dystrophy
PYC Therapeutics
NCT05573984
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
Jaeb Center for Health Research
NCT04765345
FIGHT-RP 1 Extension Study
Johns Hopkins University
NCT03999021
Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis
Ocugen
NCT05203939
Electro-acupuncture and Transcorneal Electrical Stimulation (TES) for Retinitis Pigmentosa
Nova Southeastern University
NCT02086890
Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study
Nanoscope Therapeutics
NCT06162585
CNS10-NPC for the Treatment of RP
Cedars-Sinai Medical Center
NCT04284293
Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy
University of California, Davis
NCT01736059
A Prospective, Observational Study in Adults With Retinitis Pigmentosa (RP)
Sumitomo Pharma America
NCT06517940
Study to Evaluate Safety of RTx-015 Injection in Retinitis Pigmentosa or Choroideremia Patients (ENVISION)
Ray Therapeutics
NCT06460844
Molecular Genetics of Retinal Degenerations
National Eye Institute (NEI)
NCT00231010
Trial of Oral Valproic Acid for Retinitis Pigmentosa
Foundation Fighting Blindness
NCT01233609
Observational Study to Assess the Reliability and Validity of the MLYMT and MLSDT
Nanoscope Therapeutics
NCT05820100
Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa
jCyte
NCT04604899
Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]
Nanoscope Therapeutics
NCT04945772
Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa
National Eye Institute (NEI)
NCT00065455
Object Finder for a Retinal Prosthesis
Minnesota HealthSolutions
NCT04319809
Argus II/ORCAM Device Study
Mayo Clinic
NCT03248388
Computer-Assisted Rehabilitation Environment Training After Argus Retinal Prosthesis
The Cleveland Clinic
NCT03444961
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 10 |
| Phase 2 | 4 |
| Phase 3 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Retinitis Pigmentosa Trial Landscape
ClinicalTrials.gov lists 38 US studies indexed under Retinitis Pigmentosa, and 15 of those are currently open to recruitment — roughly 39% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Retinitis Pigmentosa shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 14 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Retinitis Pigmentosa is led by National Eye Institute (NEI) with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 38 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Retinitis Pigmentosa?
PlainTrial tracks 38 US clinical trials for Retinitis Pigmentosa, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Retinitis Pigmentosa?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.