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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Retinal Vein Occlusion: early-phase trial registry

3 of 12 indexed Retinal Vein Occlusion trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 3 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Retinal Vein Occlusion: 12 US clinical trials tracked, 3 recruiting.

Retinal Vein Occlusion is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is National Eye Institute (NEI), running 3 of these trials.

Enrollment posture brief

Registry condition retinal-vein-occlusion

OPEN 3 | RECR 25% | LATE 1 | EARLY 5 | RANK #1429 | SPON 3

Nearest open-share peer: Abdominal Cancer (25% recruiting · 8 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Retinal Vein Occlusion (this)25%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Retinal Vein Occlusion

Retinal Vein Occlusion lists 3 open slots (25% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Retinal Vein Occlusion on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Retinal Vein Occlusion is recruiting below its size-band peers.

    3 of 12 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Retinal Vein Occlusion research.

    National Eye Institute (NEI) accounts for 3 of 12 trials (25%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Retinal Vein Occlusion enrolment sits around 120 participants.

    Median target enrolment is 120 among the 12 trials that report a genuine target (sentinel values excluded). 6 of those (50%) plan for fewer than 100 participants.

  4. Retinal Vein Occlusion research is mostly interventional.

    9 interventional and 3 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 22Phase 31

Open and recent trials

12 total, page 1 of 1

RECRUITING NA 1,050 participants

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Johns Hopkins University

NCT04505618

RECRUITING 650 participants

National Eye Institute Biorepository for Retinal Diseases

National Eye Institute (NEI)

NCT01496625

RECRUITING Early Phase 1 10 participants

Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium

MediBeacon

NCT04008121

ACTIVE NOT RECRUITING 6,000 participants

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

Hoffmann-La Roche

NCT05476926

COMPLETED Phase 3 1,260 participants

Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockage

National Eye Institute (NEI)

NCT00106132

COMPLETED NA 150 participants

Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion

Barnes Retina Institute

NCT01428388

COMPLETED Phase 1 120 participants

Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders

National Eye Institute (NEI)

NCT00101764

COMPLETED Phase 2 90 participants

Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)

Eyetech Pharmaceuticals

NCT00088283

COMPLETED NA 50 participants

30g vs 33g Needle for Intravitreal Injections

Wills Eye

NCT03038048

COMPLETED 32 participants

Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO

Optos

NCT01692938

COMPLETED Phase 1 21 participants

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients

Novartis Pharmaceuticals

NCT04635800

COMPLETED Phase 2 16 participants

Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion

Annexin Pharmaceuticals AB

NCT05532735

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on Retinal Vein Occlusion records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Triamcinolone Acetonide Drug
2 trials
Intravitreal injection of ranibizumab (0.5 mg per dose) Drug
1 trials
Intravitreal injection of bevacizumab Drug
1 trials
pegaptanib sodium Drug
1 trials
MHU650 Drug
1 trials
ANXV Biological
1 trials
Varying needle size with intravitreal ranibizumab or aflibercept Procedure
1 trials
Port Delivery System with Ranibizumab Combination
1 trials

US sites by state

Facility locations filed on Retinal Vein Occlusion trials. A trial with sites in several states counts in each.

Maryland 9 trials
Texas 4 trials
Michigan 3 trials
Florida 3 trials
California 3 trials
Virginia 2 trials
Pennsylvania 2 trials
Missouri 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Retinal Vein Occlusion page

12 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Retinal Vein Occlusion condition card totals 12 registered trials; most-linked intervention Triamcinolone Acetonide; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.