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ClinicalTrials.gov 3 recruiting now official registry

Retinal Vein Occlusion clinical trials

3 of 12 indexed Retinal Vein Occlusion trials are currently recruiting.

12 US clinical trials · 3 currently recruiting

Retinal Vein Occlusion is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is National Eye Institute (NEI), running 3 of these trials.

The research picture

Retinal Vein Occlusion has 12 registered US clinical trials, 3 of them open to new participants right now, about 25% of the total.

3
recruiting participants now
25%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: National Eye Institute (NEI)
Phase 13Phase 22Phase 31

Active & Recent Trials

12 total, page 1 of 1

RECRUITING NA 1,050 participants

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Johns Hopkins University

NCT04505618

RECRUITING 650 participants

National Eye Institute Biorepository for Retinal Diseases

National Eye Institute (NEI)

NCT01496625

RECRUITING Early Phase 1 10 participants

Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium

MediBeacon

NCT04008121

ACTIVE NOT RECRUITING 6,000 participants

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

Hoffmann-La Roche

NCT05476926

COMPLETED Phase 3 1,260 participants

Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockage

National Eye Institute (NEI)

NCT00106132

COMPLETED NA 150 participants

Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion

Barnes Retina Institute

NCT01428388

COMPLETED Phase 1 120 participants

Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders

National Eye Institute (NEI)

NCT00101764

COMPLETED Phase 2 90 participants

Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)

Eyetech Pharmaceuticals

NCT00088283

COMPLETED NA 50 participants

30g vs 33g Needle for Intravitreal Injections

Wills Eye

NCT03038048

COMPLETED 32 participants

Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO

Optos

NCT01692938

COMPLETED Phase 1 21 participants

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients

Novartis Pharmaceuticals

NCT04635800

COMPLETED Phase 2 16 participants

Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion

Annexin Pharmaceuticals AB

NCT05532735

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Retinal Vein Occlusion Trial Landscape

12 indexed Retinal Vein Occlusion studies · 3 recruiting (25%).

Phase mix: 1 late (III/IV) vs 5 early (I/II).

Top sponsor: National Eye Institute (NEI) (3 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Retinal Vein Occlusion?

PlainTrial tracks 12 US clinical trials for Retinal Vein Occlusion, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Retinal Vein Occlusion?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.