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NCT00000139 · ClinicalTrials.gov registry record · Phase 3

Herpetic Eye Disease Study (HEDS) II

A Phase 3 study, sponsored by National Eye Institute (NEI).

Completed
Registry status
Phase 3
Development phase

NCT00000139 is a Phase 3 study that has completed, run by National Eye Institute (NEI).

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The verdict

NCT00000139, a Phase 3 study, has completed, sponsored by National Eye Institute (NEI).

COMPLETED
Registry status
Phase 3
Development phase

Study Summary

To determine whether early treatment (with oral acyclovir) of herpes simplex virus (HSV) ulcerations of the corneal epithelium prevents progression to the blinding complications of stromal keratitis and iridocyclitis. To determine the efficacy of low-dose oral acyclovir in preventing recurrent HSV eye infection in patients with previous episodes of herpetic eye disease. To determine the role of external factors (such as ultraviolet light or corneal trauma) and behavioral factors (such as life stress) on the induction of ocular recurrences of HSV eye infections and disease.

Interventions

  • DRUG Acyclovir
  • BEHAVIORAL Stress

Trial Details

FieldValue
Start Date 1992-10
Phase Phase 3

Sponsor

National Eye Institute (NEI)

221 total trials

What the Registry Record Tells You About NCT00000139

The ClinicalTrials.gov registry entry for NCT00000139 describes a study currently listed as completed, categorized as Phase 3. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is National Eye Institute (NEI), which has 221 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Acyclovir is the first listed.

NCT00000139 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00000139 about?

NCT00000139 is a clinical study titled "Herpetic Eye Disease Study (HEDS) II". To determine whether early treatment (with oral acyclovir) of herpes simplex virus (HSV) ulcerations of the corneal epithelium prevents progression to the blinding complications of stromal keratitis and iridocyclitis. To determine the efficacy of low-dose oral acyclovir in preventing recurrent HSV ...

What is the current status of trial NCT00000139?

This trial is currently completed. It is a Phase 3 study. The study started on 1992-10.

What interventions are being tested in trial NCT00000139?

The interventions under investigation include: Acyclovir (DRUG), Stress (BEHAVIORAL).

Who is sponsoring clinical trial NCT00000139?

This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.