Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,844 total, page 3 of 57
Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors
NCT07174661
Effect of Vagal Nerve Stimulation on Gastric Motor Functions
NCT06038929
An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial
NCT06999798
Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk
NCT07207564
Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer
NCT07073794
Q702 for the Treatment of Patients With Hematologic Malignancies
NCT06712810
Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial
NCT07025369
Impact of RFA on Esophageal Distensibility and Mucosal Impedance
NCT07126535
Prehabilitation With Aerobic and Resistance Exercise for Improving Physical Fitness and Quality of Life Outcomes in Older Patients Undergoing CAR-T Therapy for Relapsed or Refractory Multiple Myeloma
NCT07045727
Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma
NCT07076472
Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy
NCT06940271
Sequential Treatments or Combinations Including Dasatinib, Quercetin, Fisetin and/or Temozolomide for the Treatment of Previously Treated Glioma With Residual Disease
NCT07025226
Ketogenic Intervention for Bipolar Depression
NCT07121894
The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults
NCT06940037
Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue Tumors, MBRT1 Trial
NCT07062003
AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness
NCT07009210
Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida
NCT06918119
Surface EMG Testing on Swallowing in EoE Patients
NCT07156357
Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists
NCT07006142
Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers
NCT07087860
Exploring the Effect of Calaspargase Pegol on the Coagulation System in Pediatric Acute Lymphoblastic Leukemia (ALL) Patients: Pilot Study
NCT07071051
Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma
NCT07091864
5-strain Probiotic Formulation in HR-positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone Loss
NCT07044310
Augmented Reality Real-Time Guidance for MRI-Guided Interventions
NCT07120906
Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
NCT06865222
WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)
NCT07058064
Management of Dyssynergic Defecation
NCT07225803
Virtual Support Platform (HERCaRE Application) for the Improvement of Survivorship Among Black Breast Cancer Survivors
NCT07126522
A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease
NCT06695247
Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)
NCT07100990
High Resolution Gastric Mapping and Gastroduodenal Manometry
NCT06941545
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
NCT06972056
Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Oral Cavity Cancer in a Rural Midwest United States Population
NCT06997068
Minnesota RETAIN Phase 3
NCT07037927
Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease
NCT06308562
A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients
NCT05803551
Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial
NCT07089927
Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers
NCT06880861
A Study of Live Tumor Fragments of Surgical Resections
NCT07000864
A Study of Paramedic HF Management
NCT06874556
Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma
NCT06940297
Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.
NCT06568549
Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)
NCT06676579
Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial
NCT06887829
App-Based Optimization of Long-Term CPAP Adherence and Quality of Life
NCT06381115
Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic Itch
NCT06751056
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus
NCT06729996
Acceptance and Commitment Therapy (ACT-HBC) for the Improvement of Cancer Distress in Patients With Hepatobiliary Cancers
NCT07124546
Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy
NCT06945380
Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial
NCT06826755
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.