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NCT07126535 · ClinicalTrials.gov registry record
Impact of RFA on Esophageal Distensibility and Mucosal Impedance
A clinical trial of Barrett Esophagus and Radiofrequency Ablation, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- 10
- Enrollment target
- 1
- Study location
NCT07126535 is a study of Barrett Esophagus and Radiofrequency Ablation that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 10 participants, below the 3,565-participant average among 32 other Barrett Esophagus trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07126535, a study of Barrett Esophagus and Radiofrequency Ablation, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients undergoing ablative therapy for management of dysplastic Barrett's Esophagus (BE) will have decreased distensibility over the course of treatment, but improvement in mucosal impedance as BE epithelia is replaced by neosquamous epithelia. This information may lead to further research in predicting therapeutic response and complications. The purpose of this research is to collect information while measuring changes related to the esophagus in patients that receive radiofrequency ablation (RFA) for dysplastic Barrett's Esophagus (BE) or esophageal cancer. Study participation includes measurements of the esophagus with the use of two different devices. This takes place during clinically indicated upper endoscopies during the timeframe the participant is receiving RFA treatments. This process will take up to an additional 10 minutes during the upper endoscopy and be done while the participant is sedated.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Radiofrequency ablation alone
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-08-19 |
| Est. Completion | 2027-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07126535
The ClinicalTrials.gov registry entry for NCT07126535 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,565-participant average among 32 other Barrett Esophagus trials with a reported enrollment target (100% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Barrett Esophagus appearing as the primary indexed condition, and to 1 intervention - of which Radiofrequency ablation alone is the first listed.
NCT07126535 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT07126535 about?
NCT07126535 is a clinical study titled "Impact of RFA on Esophageal Distensibility and Mucosal Impedance". Patients undergoing ablative therapy for management of dysplastic Barrett's Esophagus (BE) will have decreased distensibility over the course of treatment, but improvement in mucosal impedance as BE epithelia is replaced by neosquamous epithelia. This information may lead to further research in pred...
What is the current status of trial NCT07126535?
This trial is currently recruiting. The enrollment target is 10 participants. The study started on 2025-08-19. Estimated completion is 2027-07.
What conditions does trial NCT07126535 study?
This clinical trial studies the following conditions: Barrett Esophagus, Radiofrequency Ablation, Dysplastic Barrett's Esophagus.
What interventions are being tested in trial NCT07126535?
The interventions under investigation include: Radiofrequency ablation alone (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07126535?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07126535 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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