Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 2 of 57

RECRUITING NA

CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study

NCT06220396

RECRUITING NA

Ultrasound Microvessel Imaging for the Evaluation of Ovarian and Adnexal Lesions

NCT07280312

RECRUITING NA

Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables

NCT07012148

RECRUITING Phase 4

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

NCT07213466

RECRUITING NA

BLOOM: Pragmatic Feasibility Trial

NCT07287332

RECRUITING Phase 2

Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)

NCT07104812

RECRUITING Phase 4

Oral Methadone in Cardiac Surgery

NCT07221617

RECRUITING Phase 2

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

NCT06444412

RECRUITING Phase 1

Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas

NCT07456878

RECRUITING NA

WE-CARE Community Health Forums to Increase Breast Cancer Screening and Clinical Trial Participation for Rural and Low Income Women

NCT07644702

RECRUITING NA

Satisfaction and Feasibility Evaluation of an Electronic Massager Compared to Massage Therapist-delivered Massage

NCT07042776

RECRUITING Phase 1

Autologous Dendritic Cell Vaccine For Recurrent Respiratory Papillomatosis (RRP) Patients

NCT07317154

RECRUITING Phase 4

Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis

NCT07217405

RECRUITING Phase 2

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT07285044

RECRUITING

Ex Vivo Expansion (ACT-X)

NCT07137312

RECRUITING NA

One vs. Two Stents for Gallbladder Disease

NCT07222527

RECRUITING Phase 2

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

NCT07226856

RECRUITING NA

Minimal Sedation During Knee Replacement Surgery

NCT07371390

RECRUITING Phase 1

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

NCT06770023

RECRUITING NA

Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients

NCT07379138

RECRUITING NA

A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke

NCT07291024

RECRUITING

A Study Of MCG In Cardiac Amyloidosis

NCT07218705

RECRUITING

A Study of SCAD Using Stress Contrast Echocardiography

NCT07178509

RECRUITING

Impact of Physician Behavior on Cancer Distress

NCT07325006

RECRUITING NA

Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial

NCT07188532

RECRUITING Phase 4

24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients

NCT07325240

RECRUITING NA

Health and Wellness Coaching to Improve Thoracic Transplant Caregiver Self-Efficacy

NCT07361159

RECRUITING

Voices: Messages of Wisdom and Hope in the Face of Illness

NCT07381179

RECRUITING Phase 1

MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers

NCT06911008

RECRUITING NA

Comparison of Iliac Crest Marrow vs. Proximal Tibia Avitus® Bone Graft

NCT07434505

RECRUITING Phase 2

Smoking Cessation Trial in Recurrent Acute Pancreatitis and Chronic Pancreatitis

NCT07171112

RECRUITING Phase 4

The Nonirritating Concentrations of Midazolam, Ketamine, and Ondansetron

NCT07103720

RECRUITING NA

A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota

NCT07291011

RECRUITING Phase 2

The Role of Islet GLP-1 in the Pathogenesis of Prediabetes

NCT06967558

RECRUITING Phase 2

A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure

NCT07083011

RECRUITING NA

A Study Of Resilience And Mental Well-Being Through Breathing Practice For Clinical Care Professionals

NCT07218458

RECRUITING

A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

NCT07093528

RECRUITING

A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography

NCT07216469

RECRUITING NA

Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment

NCT07221409

RECRUITING Phase 2

The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes

NCT06976619

RECRUITING NA

Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control

NCT07006480

RECRUITING

Molecular and ctDNA Characterization of High-Risk Endometrial Cancer

NCT07062016

RECRUITING Phase 2

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

NCT06525766

RECRUITING NA

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

NCT07351799

RECRUITING NA

Deciphering Preserved Autonomic Function After Multiple Sclerosis

NCT07012135

RECRUITING Phase 4

Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams

NCT07164131

RECRUITING NA

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

NCT07074756

RECRUITING

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

NCT07137286

RECRUITING

Screening and Staging of Benign vs Malignant Pelvic Abnormalities

NCT07407959

RECRUITING NA

A Study Investigating the Impact of IMT With CR On Exercise Responses In HF

NCT07086131

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.