Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,816 of 2,102 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,844 total, page 4 of 57
A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers
NCT07126496
CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation
NCT06762964
HTN App for HTN Control and Cardiovascular Health Among African-Americans
NCT06346886
Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer
NCT06635980
Multi-Cancer Detection Observational Cohort Study
NCT06962995
Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy
NCT06953245
Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer
NCT06918132
AI Noise Reduction in Phonak Hearing Aids
NCT06743295
Breastmilk in Response to a Bout of Exercise
NCT06892483
In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial
NCT06704191
Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain
NCT06837857
Pharmacologic Approaches to Preventing Primary Sclerosing Cholangitis Recurrence After Liver Transplantation
NCT06905054
An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors
NCT06915727
A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening
NCT06891222
Evaluation of Plasma Renin Concentrations in Cardiac Surgery
NCT06895213
Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy
NCT06834373
Pulmonary Rehabilitation for Rural Patients With COPD
NCT06847061
Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
NCT06424106
Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion
NCT06434324
Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training
NCT06743269
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
NCT06897670
Dynamics of Organ Damage and Immune Exhaustion During Sepsis
NCT06817408
Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma
NCT06785415
Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease
NCT06952543
Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension
NCT06797193
Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer
NCT06855524
Weight Loss Through Mayo Clinic Diet
NCT06862375
Rilonacept in Subjects With Cardiac Sarcoidosis
NCT06660732
Home-based Pulmonary Rehabilitation and Health Coaching in Patients With Fibrotic Interstitial Lung Disease
NCT06751069
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
NCT06820658
A Study of a Novel Precision Medicine Approach For Obesity
NCT06814938
Sleep Restriction and Parental History of Hypertension
NCT06482814
Treatment of Upper Gastrointestinal Symptoms Using Hypnotherapy Sessions
NCT06846359
Navicam for Detection of Barrett's Esophagus
NCT06748911
Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients
NCT06824402
A Study of Hemodynamic Cardiopulmonary Exercise for CHD
NCT06566196
Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
NCT06886087
Intravenous Ketamine for Treatment-Resistant Depression
NCT06668571
A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors
NCT06831838
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
NCT06788886
Effect of Sacubitril-Valsartan on Cardiac Structure and Function
NCT06693674
Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer
NCT06625034
Knee Injections for Obese Patients With Knee Arthritis
NCT06782529
Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial
NCT06770049
Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study
NCT06770062
Real World Observational Study of Sotatercept for Pulmonary Hypertension
NCT06751082
Biomarkers of Resiliency In Childhood Cancer Surgery
NCT06674811
Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy
NCT06891209
Mechanisms of Anabolic Resistance in Older Humans
NCT06617195
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
NCT06640010
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Mayo Clinic: open-pipeline peers nationwide
Peers matched on 2,844 registered trials and 19% open enrollment, not the therapeutic-area sidebar.
Mayo Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,844 trials (± recruiting share)
- M.D. Anderson Cancer Center · 2,692 trials · 20% recruiting
- National Cancer Institute (NCI) · 3,257 trials · 10% recruiting
- Massachusetts General Hospital · 2,032 trials · 17% recruiting
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
Sponsors near 19% open enrollment (± trial volume)
- University of South Carolina · 19% recruiting · 157 trials
- Vanderbilt University Medical Center · 19% recruiting · 677 trials
- MemorialCare Health System · 19% recruiting · 21 trials
- University of North Texas Health Science Center · 19% recruiting · 21 trials
Related
What to do with this Mayo Clinic page
2,844 registered trials is a research-attention snapshot, not an endorsement of Mayo Clinic or any single study.
- 544 of Mayo Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Healthy is the condition Mayo Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Mayo Clinic pipeline card: 2,844 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.