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NCT06826755 · ClinicalTrials.gov registry record · NA
Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial
A NA study of Hypertension and Perimenopause, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06826755: Recruiting NA study of Hypertension and Perimenopause, sponsored by Mayo Clinic.
NCT06826755 is a NA study of Hypertension and Perimenopause that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 70 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06826755, a NA study of Hypertension and Perimenopause, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to study the effects of 12 weeks of melatonin supplementation compared to placebo in women who are in the menopause transition (perimenopause) and have high blood pressure.
Primary Outcome
Measured using 24-hour ambulatory blood pressure (ABP) monitoring, including nighttime BP levels and nocturnal BP dipping.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT Terry Naturally® melatonin 5mg SR
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-05-23 |
| Est. Completion | 2027-01 |
| Phase | NA |
What NCT06826755 shows while recruiting
NCT06826755 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06826755 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06826755 about?
NCT06826755 is a clinical study titled "Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial". The purpose of this research is to study the effects of 12 weeks of melatonin supplementation compared to placebo in women who are in the menopause transition (perimenopause) and have high blood pressure.
What is the current status of trial NCT06826755?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2025-05-23. Estimated completion is 2027-01.
What conditions does trial NCT06826755 study?
This clinical trial studies the following conditions: Hypertension, Perimenopause.
What interventions are being tested in trial NCT06826755?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Terry Naturally® melatonin 5mg SR (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06826755?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06826755 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06826755's enrollment target sits among peer trials
70 334th of 470 higher than 133 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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