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NCT05803551 · ClinicalTrials.gov registry record · Phase 2

A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients

A Phase 2 study of Depression, sponsored by Mayo Clinic.

Recruiting
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT05803551: Recruiting Phase 2 study of Depression, sponsored by Mayo Clinic.

NCT05803551 is a Phase 2 study of Depression that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 50 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05803551, a Phase 2 study of Depression, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research is to study the effects of intravenous ketamine infusions for the treatment of patients with depressive symptoms in intensive care unit (ICU).

Conditions Studied

Depression

Interventions

  • DRUG Placebo
  • DRUG Ketamine Hydrochloride

Study Locations (1)

Florida

  • Mayo Clinic Florida - Jacksonville

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-07-07
Est. Completion 2026-12
Phase Phase 2

Sponsor

Mayo Clinic

2,844 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05803551

The ClinicalTrials.gov registry entry for NCT05803551 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05803551 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05803551 about?

NCT05803551 is a clinical study titled "A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients". The purpose of this research is to study the effects of intravenous ketamine infusions for the treatment of patients with depressive symptoms in intensive care unit (ICU).

What is the current status of trial NCT05803551?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2025-07-07. Estimated completion is 2026-12.

What conditions does trial NCT05803551 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT05803551?

The interventions under investigation include: Placebo (DRUG), Ketamine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT05803551?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05803551 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.