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NCT06676579 · ClinicalTrials.gov registry record · Phase 2

Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)

A Phase 2 study of IgA Nephropathy (IgAN), sponsored by Mayo Clinic.

Recruiting
Registry status
Phase 2
Development phase
16
Enrollment target
2
Study locations

NCT06676579 is a Phase 2 study of IgA Nephropathy (IgAN) that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 16 participants. The trial reports 2 study locations across 2 states.

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The verdict

NCT06676579, a Phase 2 study of IgA Nephropathy (IgAN), is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
Phase 2
Development phase
16 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to evaluate the efficacy and safety of Avacopan together with low-dose glucocorticoid in the treatment of patients with crescentic Imunoglobulin A Nephropathy (IgAN) and high risk of progression.

Conditions Studied

Interventions

  • DRUG Prednisone
  • DRUG Prednisolone
  • DRUG Avacopan
  • DRUG Methylprednisolone (drug)

Study Locations (2)

Florida

  • Mayo Clinic in Florida - Jacksonville

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2025-06-09
Est. Completion 2029-03-02
Phase Phase 2

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT06676579

The ClinicalTrials.gov registry entry for NCT06676579 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with IgA Nephropathy (IgAN) appearing as the primary indexed condition, and to 4 interventions - of which Prednisone is the first listed.

NCT06676579 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Florida, Minnesota.

Frequently Asked Questions

What is clinical trial NCT06676579 about?

NCT06676579 is a clinical study titled "Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)". The purpose of this study is to evaluate the efficacy and safety of Avacopan together with low-dose glucocorticoid in the treatment of patients with crescentic Imunoglobulin A Nephropathy (IgAN) and high risk of progression.

What is the current status of trial NCT06676579?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2025-06-09. Estimated completion is 2029-03-02.

What conditions does trial NCT06676579 study?

This clinical trial studies the following conditions: IgA Nephropathy (IgAN).

What interventions are being tested in trial NCT06676579?

The interventions under investigation include: Prednisone (DRUG), Prednisolone (DRUG), Avacopan (DRUG), Methylprednisolone (drug) (DRUG).

Who is sponsoring clinical trial NCT06676579?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06676579 being conducted?

This trial has 2 study locations across Florida, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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