Edwards Lifesciences

57 total trials 10 currently recruiting 22 completed

Edwards Lifesciences sponsors 57 registered US clinical trials on ClinicalTrials.gov, 10 of them currently recruiting, and 22 completed. The most-studied condition in this pipeline is Heart Failure, with 5 trials.

Trial Pipeline

57 total, page 1 of 2

RECRUITING

HemoSphere Alta Study

NCT07148323

RECRUITING

TTVR STRONG Under Coverage With Evidence Development (CED) Study

NCT06833476

RECRUITING NA

Personal BP - CAI Study

NCT06492746

RECRUITING NA

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

NCT05172973

RECRUITING NA

TVMR With the INNOVALVE System Trial - Early Feasibility Study

NCT04919980

RECRUITING NA

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

NCT04889872

RECRUITING NA

The ENCIRCLE Trial

NCT04153292

RECRUITING NA

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

NCT04097145

RECRUITING NA

PARTNER 3 Trial - Aortic Valve-in-Valve

NCT03003299

RECRUITING NA

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

NCT02744677

ACTIVE NOT RECRUITING NA

ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System

NCT05686317

ACTIVE NOT RECRUITING

Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve

NCT05526560

ACTIVE NOT RECRUITING NA

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

NCT05172960

ACTIVE NOT RECRUITING

ALTERRA Post-Approval Study

NCT05378386

ACTIVE NOT RECRUITING NA

HPI (Hypotension Prediction Index) Care Trial

NCT05083403

ACTIVE NOT RECRUITING

COMPASSION S3 Post-Approval Study

NCT04860765

ACTIVE NOT RECRUITING NA

TRISCEND II Pivotal Trial

NCT04482062

ACTIVE NOT RECRUITING NA

Beating Heart Mitral Valve Repair With the HARPOON™ System

NCT04375332

ACTIVE NOT RECRUITING NA

2019-06 TRISCEND Study

NCT04221490

ACTIVE NOT RECRUITING NA

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

NCT03706833

ACTIVE NOT RECRUITING NA

ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis

NCT03517436

ACTIVE NOT RECRUITING NA

Early Feasibility Study - Edwards APTURE Transcatheter Shunt System

NCT03523416

ACTIVE NOT RECRUITING NA

Clinical Study of Edwards Cardioband FIT Valve Repair System

NCT03382457

ACTIVE NOT RECRUITING NA

PARTNER 3 Trial - Mitral Valve in Valve

NCT03193801

ACTIVE NOT RECRUITING NA

SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation

NCT03230747

ACTIVE NOT RECRUITING NA

ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent

NCT03130777

ACTIVE NOT RECRUITING NA

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis

NCT03042104

ACTIVE NOT RECRUITING NA

PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis

NCT02675114

ACTIVE NOT RECRUITING NA

Edwards EVOQUE Eos MISCEND Study

NCT02718001

ACTIVE NOT RECRUITING NA

ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)

NCT01757665

NOT YET RECRUITING

TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)

NCT07684313

NOT YET RECRUITING NA

Autus Valve Continued Access Study (CAS)

NCT07466745

TERMINATED NA

Hypotension Prediction Index (HPI) SMART-BP Trial

NCT05105477

COMPLETED

HUDDLE: Heart Health: Understanding & Diagnosing Disease by Leveraging Echocardiograms

NCT05009589

COMPLETED

Pediatric Cardiac Output Monitoring Observational Study

NCT04465370

COMPLETED

Hypotension Prediction Index Study (HPI Study)

NCT03805217

COMPLETED NA

Edwards CLASP TR EFS

NCT03745313

TERMINATED

RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65

NCT03680040

COMPLETED NA

Assisted Fluid Management IDE Study

NCT03469570

COMPLETED

COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction

NCT02987387

COMPLETED NA

The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study

NCT03170349

TERMINATED NA

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)

NCT03016975

COMPLETED NA

COMMENCE Pulmonary: Clinical Evaluation of Edwards Pericardial Aortic Bioprosthesis (Model 11000A) for Pulmonary Valve Replacement

NCT02656290

COMPLETED NA

Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System

NCT02471807

COMPLETED NA

PARTNER II Trial: S3iCAP

NCT02687035

COMPLETED NA

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - S3 Intermediate

NCT03222128

COMPLETED NA

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7

NCT03222141

COMPLETED NA

Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve

NCT01700439

COMPLETED NA

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve

NCT03225001

COMPLETED NA

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII B

NCT02184442

Page 1 of 2 Next →

What the Pipeline for Edwards Lifesciences Shows

According to the ClinicalTrials.gov registry, Edwards Lifesciences is linked to 57 US clinical trials across every stage of research activity. Of those, 10 studies are currently recruiting, about 18% of the sponsor's indexed portfolio, and 22 are already marked complete, representing roughly 39% of the total.

The phase mix for Edwards Lifesciences reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Edwards Lifesciences is Heart Failure with 5 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.