Dana-Farber Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Dana-Farber Cancer Institute sits in the top decile of US sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count).

781 total trials 112 currently recruiting 449 completed early-phase tilt top decile by trial count

Dana-Farber Cancer Institute: 781 sponsored US clinical trials, 112 recruiting.

Dana-Farber Cancer Institute sponsors 781 registered US clinical trials on ClinicalTrials.gov, 112 of them currently recruiting, and 449 completed. 15 of these trials are in Phase 3-4 (later-stage) and 492 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 53 trials.

Top-decile sponsor footprint

Dana-Farber Cancer Institute ranks in the top decile of sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

449 of 537 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

781 total, page 15 of 16

COMPLETED Phase 1

Donor Dendritic Cells And Donor Lymphocytes in Patients With Relapsed Hematologic Malignancies After Allogeneic Transplant

NCT00476177

COMPLETED Phase 2

Metronomic Low-Dose Cyclophosphamide and Methotrexate With or Without Bevacizumab in Treating Women With Metastatic Breast Cancer

NCT00083031

TERMINATED NA

Polyunsaturated Fatty Acids in Treating Patients With Prostate Cancer Undergoing Prostate Biopsy and/or Surgery

NCT00458549

COMPLETED Phase 2

Amifostine for Head and Neck Irradiation in Lymphoma

NCT00136474

COMPLETED NA

Educational Interventions for Patients With DCIS

NCT00148655

COMPLETED Phase 2

Randomized Amifostine For SCCHN

NCT00095927

COMPLETED NA

Preventing Adverse Drug Events With PatientSite

NCT00140504

COMPLETED Phase 2

Two Doses of Conjugated Estrogen (Premarin) in Patients With Androgen-Independent Prostate Cancer

NCT00134654

COMPLETED Phase 2

Phase II Study of Campath-1H Antibody to Treat Waldenstrom's Macroglobulinemia

NCT00142181

COMPLETED Phase 2

Tarceva, Capecitabine and Oxaliplatin for Metastatic Colorectal Cancer

NCT00123851

COMPLETED

Natural History Study of Patients With Chronic Myelogenous Leukemia

NCT00429910

COMPLETED Phase 2

Study of OSI-774 (Tarceva) in Previously Untreated Elderly Lung Cancer Patients

NCT00137800

COMPLETED Phase 2

Study of Gemcitabine and Vinorelbine in Soft Tissue Sarcomas

NCT00134641

COMPLETED Phase 2

Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT

NCT00084838

TERMINATED Phase 1

rhEndostatin Protein Involving Pediatric Patients With Cancer

NCT00165373

TERMINATED NA

High Dose Rate Intracavitary Brachytherapy as the Sole Method of Radiation Therapy for Breast Carcinoma

NCT00165581

COMPLETED Phase 2

Celecoxib (Celebrex) Versus Placebo in Men With Recurrent Prostate Cancer

NCT00136487

COMPLETED Phase 2

Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma

NCT00098865

COMPLETED Phase 2

Gemcitabine and Cisplatin for Gallbladder and Biliary Tract Cancer

NCT00123825

COMPLETED Phase 2

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation

NCT00144703

COMPLETED Phase 2

Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation

NCT00146614

COMPLETED Phase 2

Celecoxib in Preventing Cancer in Patients With Oral Leukoplakia and/or Head and Neck Dysplasia

NCT00052611

COMPLETED Phase 2

A Study in Adults With Untreated Acute Lymphoblastic Leukemia

NCT00136435

COMPLETED Phase 2

A Study of Gleevec in Patients With Idiopathic Myelofibrosis or Chronic Myelomonocytic Leukemia (CMML)

NCT00136409

COMPLETED Phase 2

Thalidomide in Combination With Temodar in Patients With Neuroendocrine Tumors

NCT00165230

COMPLETED Phase 1

Navelbine and Capecitabine in the Treatment of Metastatic Breast Cancer

NCT00153907

COMPLETED Phase 2

Letrozole in Preventing Breast Cancer in Postmenopausal Women

NCT00090857

COMPLETED Phase 2

Cisplatin, CPT-11 and Celecoxib With Radiation Therapy and Surgery for Operable Esophageal Cancer

NCT00137852

COMPLETED NA

Correlation of FC Gamma RIIIA Receptor Response in Patients With Waldenstrom's Macroglobulinemia

NCT00142155

COMPLETED Phase 2

Epirubicin and Thalidomide in Treating Patients With Liver Cancer

NCT00058487

COMPLETED Phase 1

Capecitabine or 5-Fluorouracil in Combination With Irinotecan and Cisplatin in Patients With Solid Tumor Malignancies

NCT00215501

COMPLETED Phase 2

Capecitabine and Thalidomide in Previously Treated Metastatic Colorectal Carcinoma

NCT00165217

COMPLETED

Pulmonary Function in Patients With Hodgkin's Disease Receiving Bleomycin-Based Chemotherapy

NCT00165438

COMPLETED Phase 2

Prolonged Daily Temozolomide for Low-Grade Glioma

NCT00165360

COMPLETED Phase 3

Trastuzumab in Combination With Vinorelbine or Taxane-Based Chemotherapy in Patients With Metastatic Breast Cancer

NCT00146549

COMPLETED Phase 2

Taxotere, Cisplatin and Irinotecan (CPT-11) for Esophagogastric Cancer

NCT00165464

COMPLETED NA

MRI-guided Bone Marrow Biopsies of Prostate Cancer Patients

NCT00165386

COMPLETED Phase 2

A Trial of Thalidomide, Celecoxib, Etoposide and Cyclophosphamide in Patients With Relapsed or Progressive Cancer

NCT00165451

COMPLETED Phase 2

Preoperative Herceptin and Navelbine for Breast Cancer

NCT00148681

COMPLETED NA

Tamoxifen in the Prevention of Breast Cancer in Hodgkin's Disease Survivors

NCT00165308

COMPLETED Phase 2

Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT00047294

COMPLETED Phase 2

Inhaled Morphine Compared With Morphine By Mouth in Treating Cancer Patients With Breakthrough Pain

NCT00020618

TERMINATED Early Phase 1

Vaccine Therapy in Treating Patients With Acute Lymphoblastic Leukemia

NCT00020670

COMPLETED NA

Valdecoxib in Treating Chronic Pain in Cancer Patients

NCT00021996

COMPLETED Phase 3

Methylprednisolone With or Without Daclizumab in Treating Patients With Acute Graft-Versus-Host Disease

NCT00053976

COMPLETED Phase 1

Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor

NCT00069940

COMPLETED Phase 3

Treatment of Acute Lymphoblastic Leukemia in Children

NCT00165178

COMPLETED Early Phase 1

Adjuvant Chemoradiation Therapy for Gastric or Gastroesophageal Junction Adenocarcinoma

NCT00215514

COMPLETED Phase 1

Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer

NCT00006107

COMPLETED Phase 2

Vinorelbine in Unresectable or Metastatic Esophageal and Gastric Adenocarcinoma

NCT00215462

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Phase Distribution

PhaseTrial count
Phase 1 181
Phase 2 311
Phase 3 14
Phase 4 1

What is open in the Dana-Farber Cancer Institute pipeline

112 recruiting of 781 indexed (14% open); 449 completed (57%).

Phase mix: 15 late (III/IV) vs 492 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (53 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Dana-Farber Cancer Institute: open-pipeline peers nationwide

Peers matched on 781 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share Dana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of ChicagoMedical University of South CarolinaUniversity of UtahThe Cleveland ClinicAcademic and Community Cancer Research UnitedAdaptive BiotechnologiesAgelessRx
Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 781 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Dana-Farber Cancer Institute page

781 registered trials is a research-attention snapshot, not an endorsement of Dana-Farber Cancer Institute or any single study.

  • 112 of Dana-Farber Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Dana-Farber Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Dana-Farber Cancer Institute pipeline card: 781 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.