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NCT00146614 · ClinicalTrials.gov registry record · Phase 2
Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation
A Phase 2 study, sponsored by Dana-Farber Cancer Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 105
- Enrollment target
NCT00146614: Completed Phase 2 study, sponsored by Dana-Farber Cancer Institute.
NCT00146614 is a Phase 2 study that has completed, run by Dana-Farber Cancer Institute. The registered enrollment target is 105 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (21% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00146614, a Phase 2 study, has completed, sponsored by Dana-Farber Cancer Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 105 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if the incidence of Graft vs. Host Disease (GVHD) after non-myeloablative transplantation can be reduced by using a combination of three immune suppressive medication; sirolimus, tacrolimus and methotrexate.
Interventions
- DRUG Sirolimus
- DRUG Tacrolimus
- DRUG Methotrexate
- PROCEDURE Stem Cell Transplantation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2002-07 |
| Est. Completion | 2003-04 |
| Phase | Phase 2 |
What the finished NCT00146614 record still lists
NCT00146614 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (21% lower).
The record links to 0 conditions, and to 4 interventions - of which Sirolimus is the first listed.
NCT00146614 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00146614 about?
NCT00146614 is a clinical study titled "Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation". The purpose of this study is to determine if the incidence of Graft vs. Host Disease (GVHD) after non-myeloablative transplantation can be reduced by using a combination of three immune suppressive medication; sirolimus, tacrolimus and methotrexate.
What is the current status of trial NCT00146614?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 105 participants. The study started on 2002-07. Estimated completion is 2003-04.
What interventions are being tested in trial NCT00146614?
The interventions under investigation include: Sirolimus (DRUG), Tacrolimus (DRUG), Methotrexate (DRUG), Stem Cell Transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT00146614?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00146614's enrollment target sits among peer trials
105 650th of 2000 higher than 1,341 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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