Dana-Farber Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Dana-Farber Cancer Institute sits in the top decile of US sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count).

781 total trials 112 currently recruiting 449 completed early-phase tilt top decile by trial count

Dana-Farber Cancer Institute: 781 sponsored US clinical trials, 112 recruiting.

Dana-Farber Cancer Institute sponsors 781 registered US clinical trials on ClinicalTrials.gov, 112 of them currently recruiting, and 449 completed. 15 of these trials are in Phase 3-4 (later-stage) and 492 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 53 trials.

Top-decile sponsor footprint

Dana-Farber Cancer Institute ranks in the top decile of sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

449 of 537 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

781 total, page 16 of 16

COMPLETED Phase 2

Defibrotide in Treating Patients With Liver Damage Following Peripheral Stem Cell Transplantation

NCT00003966

COMPLETED Phase 1

Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy

NCT00005988

COMPLETED Phase 1

Study of Vaccination With Autologous Acute Myeloblastic Leukemia Cells in Patients With Advanced Myelodysplasia or Acute Myelogenous Leukemia

NCT00136422

COMPLETED NA

Dynamic Area Telethermometry (DAT) as an Imaging Modality in Patients With Cancer

NCT00165100

COMPLETED Phase 2

Docetaxel in Treating Patients With Stage II or Stage III Prostate Cancer

NCT00005096

COMPLETED Phase 2

Trastuzumab in Treating Patients With Advanced Salivary Gland Cancer

NCT00004163

COMPLETED Phase 2

Rosiglitazone in Treating Patients With Liposarcoma

NCT00004180

COMPLETED Phase 1

Taxotere, Cisplatin, and CPT-11 in Advanced Solid Tumor Malignancies

NCT00251407

COMPLETED Phase 1

Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma

NCT00165555

COMPLETED Phase 1

Gene Therapy in Treating Patients With Unresectable, Recurrent, or Refractory Head and Neck Cancer

NCT00004070

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Metastatic Breast Cancer

NCT00003761

COMPLETED Phase 1

Estramustine, Docetaxel, and Carboplatin in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy

NCT00005627

COMPLETED Phase 2

Gemcitabine in Treating Patients With Advanced Salivary Gland Cancer That Cannot Be Removed During Surgery

NCT00003744

COMPLETED Phase 2

Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer

NCT00165243

COMPLETED Phase 2

Doxorubicin, Cisplatin, 5-Fluorouracil in Patients With Advanced Adenocarcinoma of the Stomach or Esophagus

NCT00165191

COMPLETED NA

Counseling Interventions for BRCA 1/2 Cancer Susceptibility Testing

NCT00165152

COMPLETED Phase 2

High-dose ICE With Amifostine

NCT00003657

COMPLETED

A-protein Levels in Adult and Pediatric Brain Tumor Patients

NCT00165542

COMPLETED Phase 1

Gemcitabine, 5-Fluorouracil, and Radiation Therapy in the Treatment of Non-Metastatic Pancreatic Cancer

NCT00251355

COMPLETED Phase 1

Study of Taxotere, Cisplatin, 5-Fluorouracil, and Leucovorin for Squamous Cell Carcinoma of the Head and Neck

NCT00139243

COMPLETED Phase 2

Troglitazone in Treating Patients With Liposarcoma

NCT00003058

COMPLETED Phase 2

A Study of All-Trans Retinoic Acid (ATRA) and Bryostatin in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

NCT00136461

COMPLETED NA

Hyperthermia Plus Radiation Therapy in Treating Patients With Nonmetastatic Advanced Prostate Cancer

NCT00003045

COMPLETED Phase 2

Combination Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck

NCT00139230

COMPLETED Phase 2

Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas

NCT00165139

TERMINATED Phase 3

Treatment of Childhood Acute Lymphoblastic Leukemia

NCT00165087

COMPLETED Phase 1

Chemotherapy Plus Radiation Therapy in Treating Patients With Squamous Cell Cancer of the Head and Neck

NCT00003200

COMPLETED Phase 3

Study of External Beam Radiation Therapy With and Without Hormonal Therapy to Treat Prostate Cancer

NCT00116220

COMPLETED Phase 1

Multicenter Study of 9-Aminocamptothecin (9-AC) in Patients With Refractory Leukemia

NCT00251368

COMPLETED Phase 2

High Dose Ara-C (HDAC) and Interleukin-2 (IL-2) for Patients With Acute Myelogenous Leukemia (AML)

NCT00136448

COMPLETED Phase 2

Mantle Irradiation for Hodgkin's Disease

NCT00165269

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Phase Distribution

PhaseTrial count
Phase 1 181
Phase 2 311
Phase 3 14
Phase 4 1

What is open in the Dana-Farber Cancer Institute pipeline

112 recruiting of 781 indexed (14% open); 449 completed (57%).

Phase mix: 15 late (III/IV) vs 492 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (53 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Dana-Farber Cancer Institute: open-pipeline peers nationwide

Peers matched on 781 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share Dana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of ChicagoMedical University of South CarolinaUniversity of UtahThe Cleveland ClinicAcademic and Community Cancer Research UnitedAdaptive BiotechnologiesAgelessRx
Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 781 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Dana-Farber Cancer Institute page

781 registered trials is a research-attention snapshot, not an endorsement of Dana-Farber Cancer Institute or any single study.

  • 112 of Dana-Farber Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Dana-Farber Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Dana-Farber Cancer Institute pipeline card: 781 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.