Dana-Farber Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Dana-Farber Cancer Institute sits in the top decile of US sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count).

781 total trials 112 currently recruiting 449 completed early-phase tilt top decile by trial count

Dana-Farber Cancer Institute: 781 sponsored US clinical trials, 112 recruiting.

Dana-Farber Cancer Institute sponsors 781 registered US clinical trials on ClinicalTrials.gov, 112 of them currently recruiting, and 449 completed. 15 of these trials are in Phase 3-4 (later-stage) and 492 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 53 trials.

Top-decile sponsor footprint

Dana-Farber Cancer Institute ranks in the top decile of sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

449 of 537 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

781 total, page 14 of 16

COMPLETED Phase 2

Using Positron Emission Tomography to Evaluate the Effects of Bevacizumab on Intra-tumoral Pharmacokinetics of 5-fluorouracil in Metastatic Colorectal Cancer

NCT00165568

TERMINATED Phase 2

Intensive Chemotherapy and Rituximab in the Treatment of Burkitt Lymphoma

NCT00126191

COMPLETED Phase 2

Cetuximab and Vinorelbine in Elderly Subjects With Lung Cancer

NCT00165334

COMPLETED Phase 1

Laboratory-Treated Lymphocyte Infusion After Haploidentical Donor Stem Cell Transplant

NCT00376480

COMPLETED Phase 3

Hormone Suppression and Radiation Therapy for 6 Months With/Without Docetaxel for High Risk Prostate Cancer

NCT00116142

COMPLETED Phase 3

05-001: Treatment of Acute Lymphoblastic Leukemia in Children

NCT00400946

COMPLETED Phase 3

Computerized Assessment for Patients With Cancer

NCT00194493

COMPLETED NA

Evaluation of the Effects of Chemotherapy on the Uptake and Retention of Carbon 11 Methionine in Prostate Cancer Patients

NCT00139204

COMPLETED Phase 2

Chemotherapy Followed by Zevalin for Relapsed Mantle Cell Lymphoma

NCT00119730

COMPLETED Phase 2

Mifepristone (RU-486) in Androgen Independent Prostate Cancer

NCT00140478

COMPLETED Phase 2

Study of Bevacizumab, Erlotinib, FOLFOX for Patients With Untreated Metastatic Colorectal Cancer

NCT00116506

COMPLETED Phase 1

Vaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV Melanoma

NCT00258687

COMPLETED Phase 2

Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer

NCT00357500

COMPLETED Phase 2

Bevacizumab in Combination With Temozolomide in Patients With Neuroendocrine Tumors

NCT00137774

COMPLETED NA

The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology

NCT01838564

COMPLETED

Upstaging of ALH/LCIS Found on Core Biopsy Based on Subsequent Excisional Biopsy

NCT00146536

COMPLETED Phase 2

Study of Xyotax (CT-2103) in Patients With Metastatic Breast Cancer

NCT00148707

COMPLETED Phase 2

Docetaxel in Combination With Iressa in Previously Treated Patients With Pancreatic Cancer

NCT00137761

TERMINATED Phase 2

Title XELOX FOR SALIVARY GLAND CANCERS

NCT00101075

TERMINATED Phase 2

Capecitabine in Women With Operable Breast Cancer

NCT00148720

TERMINATED Phase 2

CC-5013 (Lenalidomide) and Rituximab in Waldenstrom's Macroglobulinemia

NCT00142168

COMPLETED Phase 3

Combination Chemotherapy and Radiation in Treating Patients With Stage III or IV Head and Neck Cancer (Paradigm Trial)

NCT00095875

COMPLETED Phase 2

Combination Chemotherapy, Radiation Therapy and Surgery for Esophageal Cancer

NCT00165490

COMPLETED Phase 2

Avastin and Taxotere for Esophagogastric Cancer

NCT00137813

COMPLETED Phase 1

Bortezomib in Combination With CC-5013 in Patients With Relapsed/Refractory Multiple Myeloma

NCT00153933

COMPLETED Phase 2

Preoperative Cisplatin in Early Stage Breast Cancer

NCT00148694

COMPLETED Phase 2

Study of Dynavax's 1018 ISS, Following Rituxan in Patients With B-Cell Follicular Lymphoma

NCT00251394

COMPLETED Phase 2

Capecitabine For Nasopharyngeal Cancer

NCT00095901

COMPLETED NA

GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies

NCT00426205

COMPLETED Phase 2

Fulvestrant in Premenopausal Women With Hormone Receptor-Positive Breast Cancer

NCT00146601

COMPLETED Phase 2

Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy

NCT00165204

COMPLETED

Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major

NCT00480506

TERMINATED Phase 2

Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate

NCT00165503

COMPLETED Phase 2

Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies

NCT00153985

COMPLETED Phase 2

Thalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignant Glioma

NCT00047281

COMPLETED Phase 2

Docetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local Treatment

NCT00165399

COMPLETED Phase 2

Bevacizumab (Avastin) and Erlotinib (Tarceva) in Previously Treated Mesothelioma

NCT00137826

COMPLETED Phase 1

Rituximab Therapy for Steroid-Refractory Chronic Graft Versus Host Disease

NCT00136396

COMPLETED

Dosimetric Analysis of Vaginal Cuff Brachytherapy in Endometrial Carcinoma

NCT00165126

COMPLETED Phase 2

Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate

NCT00165516

COMPLETED Phase 2

A Study of Docetaxel Plus Carboplatin in Patients With Hormone Refractory Prostate Cancer

NCT00134706

COMPLETED Phase 2

Fludarabine and Rituximab for the Treatment of Marginal Zone Non-Hodgkin's Lymphoma

NCT00117156

COMPLETED Phase 2

Bortezomib (Velcade) in Waldenstrom's Macroglobulinemia

NCT00142129

COMPLETED Phase 2

Protein Tyrosine Kinases (PTK) in Multiple Myeloma

NCT00165347

COMPLETED Phase 1

Talotrexin in Treating Patients With Advanced or Recurrent Solid Tumors

NCT00098514

COMPLETED Phase 2

Bortezomib (Velcade) in Patients With Untreated Multiple Myeloma

NCT00153920

COMPLETED NA

Effects of Exercise Intervention on Insulin Levels in Breast Cancer Survivors

NCT00153894

COMPLETED Phase 2

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

NCT00144677

COMPLETED Phase 1

Vaccination With Autologous, Lethally Irradiated Melanoma Cells Engineered by Adenoviral Mediated Gene Transfer to Secrete Granulocyte-Macrophage Stimulating Factor (GMSF)

NCT00809588

COMPLETED Phase 2

Tarceva and Capecitabine for Pancreatic Cancer

NCT00125021

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Phase Distribution

PhaseTrial count
Phase 1 181
Phase 2 311
Phase 3 14
Phase 4 1

What is open in the Dana-Farber Cancer Institute pipeline

112 recruiting of 781 indexed (14% open); 449 completed (57%).

Phase mix: 15 late (III/IV) vs 492 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (53 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Dana-Farber Cancer Institute: open-pipeline peers nationwide

Peers matched on 781 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share Dana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of ChicagoMedical University of South CarolinaUniversity of UtahThe Cleveland ClinicAcademic and Community Cancer Research UnitedAdaptive BiotechnologiesAgelessRx
Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 781 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Dana-Farber Cancer Institute page

781 registered trials is a research-attention snapshot, not an endorsement of Dana-Farber Cancer Institute or any single study.

  • 112 of Dana-Farber Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Dana-Farber Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Dana-Farber Cancer Institute pipeline card: 781 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.