Dana-Farber Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Dana-Farber Cancer Institute sits in the top decile of US sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count).

781 total trials 112 currently recruiting 449 completed early-phase tilt top decile by trial count

Dana-Farber Cancer Institute: 781 sponsored US clinical trials, 112 recruiting.

Dana-Farber Cancer Institute sponsors 781 registered US clinical trials on ClinicalTrials.gov, 112 of them currently recruiting, and 449 completed. 15 of these trials are in Phase 3-4 (later-stage) and 492 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 53 trials.

Top-decile sponsor footprint

Dana-Farber Cancer Institute ranks in the top decile of sponsors by registered trial count (#42 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

449 of 537 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

781 total, page 2 of 16

RECRUITING NA

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

NCT05740839

RECRUITING Early Phase 1

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

NCT06122896

RECRUITING NA

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

NCT06038318

RECRUITING NA

A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

NCT05899361

RECRUITING NA

Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

NCT05706766

RECRUITING Phase 2

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

NCT05726370

RECRUITING Phase 2

Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia

NCT05734495

RECRUITING NA

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

NCT05759143

RECRUITING

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

NCT05463796

RECRUITING NA

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

NCT05535192

RECRUITING NA

A Novel Intervention for Patients With Cancer

NCT05643027

RECRUITING NA

Patient-Centered Surgical Prehabilitation

NCT05715684

RECRUITING

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

NCT05587439

RECRUITING

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

NCT05265429

RECRUITING NA

Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

NCT05356117

RECRUITING NA

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

NCT05327465

RECRUITING NA

Video Education With Result Dependent dIsclosure

NCT05225428

RECRUITING NA

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

NCT05335434

RECRUITING NA

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

NCT05236062

RECRUITING NA

Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

NCT04997096

RECRUITING Phase 2

Zanubrutinib and Venetoclax in CLL (ZANU-VEN)

NCT05168930

RECRUITING NA

UPLYFT For Lymphoma Survivors

NCT05080166

RECRUITING NA

Resilience and Equity in Aging, Cancer, and Health (REACH)

NCT04674267

RECRUITING Phase 1

NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma

NCT04930783

RECRUITING NA

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

NCT04883671

RECRUITING Phase 2

Scalp Cooling in MBC

NCT04986579

RECRUITING NA

Geriatric Thoracic Surgery Ambulation Challenge

NCT04630496

RECRUITING Phase 1

A Personalized Neoantigen Cancer Vaccine in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated CLL.

NCT03219450

RECRUITING NA

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

NCT04839614

RECRUITING NA

Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy

NCT04724499

RECRUITING Phase 2

ATEMPT 2.0: Adjuvant T-DM1 vs TH

NCT04893109

RECRUITING

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

NCT04968834

RECRUITING NA

Refining Local-Regional Therapy for IBC

NCT04636710

RECRUITING Phase 1

Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer

NCT04789486

RECRUITING Phase 1

Sacituzumab Govitecan Plus EV in Metastatic UC

NCT04724018

RECRUITING Phase 1

IS-free Treg HaploHCT

NCT04678401

RECRUITING Phase 2

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer

NCT04569747

RECRUITING Phase 2

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

NCT04620187

RECRUITING

Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress

NCT04541654

RECRUITING Phase 1

Pembrolizumab, Ibrutinib and Rituximab in PCNSL

NCT04421560

RECRUITING Phase 2

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

NCT04468061

RECRUITING Phase 2

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

NCT04434040

RECRUITING NA

Serial MRI Scans During Radiation Therapy

NCT04188535

RECRUITING NA

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

NCT04045470

RECRUITING NA

Stereotactic Magnetic Resonance Guided Radiation Therapy

NCT04115254

RECRUITING Phase 1

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

NCT04024761

RECRUITING NA

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

NCT03875716

RECRUITING Phase 2

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer

NCT03675893

RECRUITING

Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)

NCT03689595

RECRUITING NA

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

NCT03683680

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Phase Distribution

PhaseTrial count
Phase 1 181
Phase 2 311
Phase 3 14
Phase 4 1

What is open in the Dana-Farber Cancer Institute pipeline

112 recruiting of 781 indexed (14% open); 449 completed (57%).

Phase mix: 15 late (III/IV) vs 492 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (53 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Dana-Farber Cancer Institute: open-pipeline peers nationwide

Peers matched on 781 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share Dana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of ChicagoMedical University of South CarolinaUniversity of UtahThe Cleveland ClinicAcademic and Community Cancer Research UnitedAdaptive BiotechnologiesAgelessRx
Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Dana-Farber Cancer Institute sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 781 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Dana-Farber Cancer Institute page

781 registered trials is a research-attention snapshot, not an endorsement of Dana-Farber Cancer Institute or any single study.

  • 112 of Dana-Farber Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Dana-Farber Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Dana-Farber Cancer Institute pipeline card: 781 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.