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NCT07675967 · ClinicalTrials.gov registry record
Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
A clinical trial, sponsored by Dana-Farber Cancer Institute.
- Recruiting
- Registry status
- 5,000
- Enrollment target
NCT07675967: Recruiting study, sponsored by Dana-Farber Cancer Institute.
NCT07675967 is a clinical trial that is actively recruiting participants, run by Dana-Farber Cancer Institute. The registered enrollment target is 5,000 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07675967 is actively recruiting participants, sponsored by Dana-Farber Cancer Institute.
- RECRUITING
- Registry status
- 5,000 participants
- Enrollment target
Study Summary
The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (CH) influences outcomes in people receiving chemotherapy and radiation for solid cancers. The study will collect biospecimens and clinical information. These data will be used to define clinical and molecular features that predict the presence of high-risk clonal hematopoiesis (CH) in patients exposed to cytotoxic anti-cancer therapy. Predictive features will be utilized to identify populations of cancer patients and survivors who are at the highest risk of developing therapy-related myeloid neoplasms (t-MNs). Ultimately this study will result in the development of a novel novel risk prediction algorithm for t-MNs in patients with solid cancers and drive potential therapeutic approaches to intercept progression from CH to often fatal t-MNs.
Primary Outcome
Prevalence of clonal hematopoiesis detected by the study's targeted unique molecular identifier-based sequencing panel in population of adults with advanced non-metastatic solid cancers.
Interventions
- OTHER Samples
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,000 participants |
| Start Date | 2025-04-04 |
| Est. Completion | 2035-03-31 |
What NCT07675967 shows while recruiting
NCT07675967 is an observational study that tracks outcomes without assigning an intervention. Its 5,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 1 intervention - of which Samples is the first listed.
NCT07675967 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07675967 about?
NCT07675967 is a clinical study titled "Clonal Hematopoiesis Chemotherapy and Radiation Effects Study". The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (CH) influences outcomes in people receiving chemotherapy and radiation for solid cancers. The study will collect biospecimens and clinical in...
What is the current status of trial NCT07675967?
This trial is currently recruiting. The enrollment target is 5,000 participants. The study started on 2025-04-04. Estimated completion is 2035-03-31.
What interventions are being tested in trial NCT07675967?
The interventions under investigation include: Samples (OTHER).
Who is sponsoring clinical trial NCT07675967?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
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