Columbia University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Columbia University sits in the top decile of US sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count).

958 total trials 171 currently recruiting 597 completed early-phase tilt top decile by trial count

Columbia University: 958 sponsored US clinical trials, 171 recruiting.

Columbia University sponsors 958 registered US clinical trials on ClinicalTrials.gov, 171 of them currently recruiting, and 597 completed. 88 of these trials are in Phase 3-4 (later-stage) and 191 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 9 trials.

Top-decile sponsor footprint

Columbia University ranks in the top decile of sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

597 of 736 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

958 total, page 18 of 20

COMPLETED

Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)

NCT00537641

COMPLETED NA

Using Multimedia Technologies to Disseminate an HIV Prevention

NCT01863537

COMPLETED NA

A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents

NCT00461487

TERMINATED Phase 2

Sunitinib in Certain Subtypes of Soft Tissue Sarcomas

NCT00859456

COMPLETED

The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion

NCT00494598

TERMINATED NA

Effect of Raised CBF During CEA on Cognition in DM Patients

NCT00597545

TERMINATED Phase 4

Adult Growth Hormone Deficiency and Cardiovascular Risk

NCT00720902

COMPLETED

Sensitivity and Specificity of NGAL in an Emergency Room Population

NCT00786708

COMPLETED

Bariatric Surgery for Morbid Obesity

NCT00675558

COMPLETED Phase 4

Effects of Sandostatin LAR® in Acromegaly

NCT01424241

COMPLETED NA

Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease

NCT01137955

COMPLETED

Body Composition & REE Responses to Bariatric Surgery

NCT00682058

COMPLETED Phase 3

A Randomized Trial of Unruptured Brain AVMs

NCT00389181

TERMINATED

General Surgery Training Outcomes Project

NCT00461214

TERMINATED

Fundic Gland Polyps and Proton Pump Inhibitor (PPI) Drugs

NCT01130363

COMPLETED

Role of B2 Adrenergic Receptors in Labor Pain

NCT00385294

COMPLETED NA

Written Asthma Actions Plans Versus No Written Instructions In Specialty Care

NCT00149461

COMPLETED

PET Scan Imaging of Beta Cell Mass

NCT00771576

COMPLETED

Race, Ethnicity, and Diffuse Parenchymal Lung Disease

NCT00453713

COMPLETED Phase 2

Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis

NCT00355576

COMPLETED Phase 4

Obesity, Oral Contraception, and Ovarian Suppression

NCT00827632

TERMINATED Phase 1

Study of Bevacizumab and Erlotinib for Patients With Hormone Refractory Prostate Cancer

NCT00996502

COMPLETED NA

Framing and Decision Making in Neonatology

NCT01421238

COMPLETED Phase 1

Adefovir Plus Vaccination in Transplant Patients Without Hepatitis B That Receive a Core Antibody Positive Liver

NCT01146808

COMPLETED

Single-Breath Measurement Underestimates Ventilatory Volume According to Emphysema Severity

NCT00528944

TERMINATED NA

Operating Room Outcomes After Resident Training on a Virtual Reality Simulator

NCT00459472

COMPLETED Phase 4

Nicotine Patch as an Analgesic Adjuvant After Surgery

NCT00440830

COMPLETED Phase 2

Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation

NCT00297830

COMPLETED NA

HIV/STI Prevention for Drug-Involved Couples

NCT01285349

COMPLETED

Primary Hyperparathyroidism: Non-classical Manifestations

NCT00432939

COMPLETED Phase 1

Neuroprotection With Statin Therapy for Acute Recovery Trial (Neu-START)

NCT00243880

COMPLETED Phase 2

Capecitabine and Temozolomide for Neuroendocrine Cancers

NCT00869050

COMPLETED Phase 2

Alimta Plus Gemcitabine for Advanced Sarcoma

NCT00860015

COMPLETED Phase 1

The Effect of Cinnamon Extract on Insulin Resistance Parameters in Polycystic Ovary Syndrome: A Pilot Study

NCT00331279

COMPLETED Phase 4

Efficacy and Safety Study of Tazarotene (Tazorac) for the Treatment of Brittle Nails

NCT00648986

COMPLETED Phase 1

Study of Lenalidomide and Docetaxel in Subjects With Androgen Independent Prostate Cancer

NCT01378091

COMPLETED

Coronary Heart Disease Incidence: Depression & Inflammation Risk

NCT00241774

TERMINATED Phase 2

GTX Regimen for Biliary Cancers

NCT00868998

COMPLETED

Levels of Inflammatory Markers in the Treatment of Stroke-An SPS3 Ancillary Study

NCT00579306

COMPLETED Phase 2

Intravenous Immunoglobulin (IVIG) in Lung Transplantation

NCT00115778

COMPLETED Phase 2

Study for Inoperable Non-Metastatic Pancreatic CA (Stage IVA) With Neoadjuvant GTX, and Radiation With Gemzar

NCT00869258

COMPLETED NA

Acupuncture for Aromatase Inhibitor Induced Joint Pain

NCT00826397

COMPLETED NA

Project Hope: Hospital Visit is an Opportunity for Prevention and Engagement With HIV-positive Crack Users

NCT00447798

COMPLETED

Clinical Study of Spinal Muscular Atrophy

NCT00443066

COMPLETED Phase 2

Clinical Trial of High Dose CoQ10 in ALS

NCT00243932

COMPLETED

Changes in Insulin Sensitivity After Weight Loss

NCT00627484

TERMINATED Phase 2

The Stroke Warning Information and Faster Treatment Study (SWIFT)

NCT00415389

COMPLETED NA

COPES Phase I Randomized Controlled Trial of Treatment For Distress in Heart Disease Patients

NCT00158054

COMPLETED NA

Evaluating the Effectiveness of a Family Heart Health Educational Program (The FIT-Heart Study)

NCT00728637

COMPLETED NA

Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention

NCT01236248

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Phase Distribution

PhaseTrial count
Phase 1 86
Phase 2 105
Phase 3 23
Phase 4 65

What is open in the Columbia University pipeline

171 recruiting of 958 indexed (18% open); 597 completed (62%).

Phase mix: 88 late (III/IV) vs 191 early (I/II) (early-phase heavy).

Top condition: Obesity (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Columbia University: open-pipeline peers nationwide

Peers matched on 958 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Columbia UniversityUniversity of MinnesotaBrigham and Women's HospitalHoffmann-La RocheUniversity of California, Los AngelesKite, A Gilead CompanyMirum PharmaceuticalsWest Virginia UniversityHospital for Special Surgery, New York
Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 958 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Columbia University page

958 registered trials is a research-attention snapshot, not an endorsement of Columbia University or any single study.

  • 171 of Columbia University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Columbia University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Columbia University pipeline card: 958 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.