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NCT00675558 · ClinicalTrials.gov registry record
Bariatric Surgery for Morbid Obesity
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 50
- Enrollment target
NCT00675558 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 50 participants.
The verdict
NCT00675558 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
Despite progress in understanding the pathophysiology of obesity, current strategies for its medical management remain largely ineffective. Most efforts have focused on reducing caloric intake or increasing energy expenditure, either through behavior modification (e.g. dieting, regular exercise) alone, or augmented by pharmacologic efforts to decrease appetite, inhibit fat absorption, or alter metabolism. Bariatric surgery remains the only proven long term treatment of morbid obesity. Super morbidly obese (SMO: Body Mass Index (BMI) \> 50) and super super morbidly obese (SSMO: BMI \> 60) patients lose considerable weight, but stabilize at Body Mass Indexes (BMIs) that are still obese or even morbidly obese after risking considerable morbidity and/or mortality. Among commonly performed bariatric surgeries, a laparoscopic two-stage procedure, in which an initial restrictive procedure is followed after a weight loss of \~100 lbs by a more complex procedure that creates malabsorption, is gaining interest. Initial studies have demonstrated very good long-term weight loss with minimal morbidity, and no operative mortality in these high risk patients. Availability of biospecimens obtained at each stage of this protocol will allow participating scientists a unique opportunity to test in human tissues hypotheses developed in animals. Studies proposed under this application focus on fatty acids and overall fat disposition in fat depots (adipose tissue) of your body, and the role of adipose tissue hormones and inflammatory processes in obesity and its associated health related issues.
Interventions
- PROCEDURE Initial Surgery
- PROCEDURE Second Bariatric Surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2006-11 |
| Est. Completion | 2012-03 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00675558
The ClinicalTrials.gov registry entry for NCT00675558 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Initial Surgery is the first listed.
NCT00675558 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00675558 about?
NCT00675558 is a clinical study titled "Bariatric Surgery for Morbid Obesity". Despite progress in understanding the pathophysiology of obesity, current strategies for its medical management remain largely ineffective. Most efforts have focused on reducing caloric intake or increasing energy expenditure, either through behavior modification (e.g. dieting, regular exercise) alo...
What is the current status of trial NCT00675558?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2006-11. Estimated completion is 2012-03.
What interventions are being tested in trial NCT00675558?
The interventions under investigation include: Initial Surgery (PROCEDURE), Second Bariatric Surgery (PROCEDURE).
Who is sponsoring clinical trial NCT00675558?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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