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NCT00494598 · ClinicalTrials.gov registry record

The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion

A clinical trial of Aortic Aneurysm, sponsored by Columbia University.

Completed
Registry status
6
Enrollment target
1
Study location

NCT00494598: Completed study of Aortic Aneurysm, sponsored by Columbia University.

NCT00494598 is a study of Aortic Aneurysm that has completed, run by Columbia University. The registered enrollment target is 6 participants, below the 639-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00494598, a study of Aortic Aneurysm, has completed, sponsored by Columbia University.

COMPLETED
Registry status
6 participants
Enrollment target
1
Study location

Study Summary

There is a need to understand how long anesthetic drugs last in the brain during surgery on the ascending aorta or aortic arch. Drugs can have a prolonged effect when blood temperature is made cold therefore the influence of temperature needs to be studied. This type of surgery allows us to answer questions about how anesthetic drugs behave when they are given during a routine portion of surgery. Patients will be provided with anesthetic drugs during surgery while on a heart lung machine. After the drug is injected into the heart lung machine it will be delivered to the brain to provide more sleep and pain relief. Immediately after the injection of anesthetic drugs, blood samples will be taken from an existing intravenous line in the neck and plasma drug concentrations measured. This will help us to understand how long drugs last in the brain during this type of surgery.

Conditions Studied

Interventions

  • DRUG Sufentanil

Study Locations (1)

New York

  • Columbia University College of Physicians and Surgeons - New York

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2007-03
Est. Completion 2007-06
Columbia University

958 total trials

What the finished NCT00494598 record still lists

NCT00494598 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 639-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Aortic Aneurysm appearing as the primary indexed condition, and to 1 intervention - of which Sufentanil is the first listed.

NCT00494598 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00494598 about?

NCT00494598 is a clinical study titled "The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion". There is a need to understand how long anesthetic drugs last in the brain during surgery on the ascending aorta or aortic arch. Drugs can have a prolonged effect when blood temperature is made cold therefore the influence of temperature needs to be studied. This type of surgery allows us to answer q...

What is the current status of trial NCT00494598?

This trial is currently completed. The enrollment target is 6 participants. The study started on 2007-03. Estimated completion is 2007-06.

What conditions does trial NCT00494598 study?

This clinical trial studies the following conditions: Aortic Aneurysm.

What interventions are being tested in trial NCT00494598?

The interventions under investigation include: Sufentanil (DRUG).

Who is sponsoring clinical trial NCT00494598?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00494598 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Aortic Aneurysm

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00494598's enrollment target sits among peer trials

6 15th of 14 the lowest of 14 other Aortic Aneurysm trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aortic Aneurysm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00494598, the US trial registry maintained by the National Library of Medicine. NCT00494598 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.