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NCT00537641 · ClinicalTrials.gov registry record
Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)
A clinical trial of Amyotrophic Lateral Sclerosis and Motor Neuron Disease, sponsored by Columbia University.
- Completed
- Registry status
- 25
- Enrollment target
- 1
- Study location
NCT00537641: Completed study of Amyotrophic Lateral Sclerosis and Motor Neuron Disease, sponsored by Columbia University.
NCT00537641 is a study of Amyotrophic Lateral Sclerosis and Motor Neuron Disease that has completed, run by Columbia University. The registered enrollment target is 25 participants, below the 898-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00537641, a study of Amyotrophic Lateral Sclerosis and Motor Neuron Disease, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test the hypothesis that noninvasive ventilation (NIV) as prescribed in current medical practice for use in amyotrophic Lateral Sclerosis (ALS) patients fails to deliver adequate breathing support over a night of use in the patient's home. ALS patients who come to the ALS Center for their routine 3 month follow up exam and are currently using NIV will be asked to complete questionnaires regarding their quality of sleep, quality of life and general level of function, and to undergo a home sleep study, using a safe, comfortable and reliable breathing monitoring system during a night of sleep. If the questionnaires or the sleep study show failure of the breathing device, the investigators will work with the patient to fix the problem and then offer a second study to make sure that the changes were helpful. The results of this study may help to develop subsequent studies and to improve the guidelines used for care of ALS patients.
Primary Outcome
The ALS Functional Rating Scale - Revised (ALSFRS-R) will be administered to measure tolerance.
Conditions Studied
Study Locations (1)
New York
- Eleanor and Lou Gehrig ALS/MDA Center at Columbia University - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2007-05 |
| Est. Completion | 2011-06 |
What the finished NCT00537641 record still lists
NCT00537641 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 898-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 0 interventions.
NCT00537641 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00537641 about?
NCT00537641 is a clinical study titled "Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)". This study will test the hypothesis that noninvasive ventilation (NIV) as prescribed in current medical practice for use in amyotrophic Lateral Sclerosis (ALS) patients fails to deliver adequate breathing support over a night of use in the patient's home. ALS patients who come to the ALS Center for ...
What is the current status of trial NCT00537641?
This trial is currently completed. The enrollment target is 25 participants. The study started on 2007-05. Estimated completion is 2011-06.
What conditions does trial NCT00537641 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis, Motor Neuron Disease.
Who is sponsoring clinical trial NCT00537641?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00537641 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyotrophic Lateral Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00537641's enrollment target sits among peer trials
25 70th of 102 higher than 31 of 102 other Amyotrophic Lateral Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amyotrophic Lateral Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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