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NCT00528944 · ClinicalTrials.gov registry record
Single-Breath Measurement Underestimates Ventilatory Volume According to Emphysema Severity
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 73
- Enrollment target
NCT00528944: Completed study, sponsored by Columbia University.
NCT00528944 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 73 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00528944 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 73 participants
- Enrollment target
Study Summary
Although single breath helium (He) dilution measurement (VASB) is currently used in pulmonary function laboratories to assess functional alveolar volume and diffusing capacity for carbon monoxide, the extent to which VASB reflects ventilatory and thoracic volume has not been prospectively determined in emphysema. We hypothesized that VASB underestimates rebreathe helium dilution volume (VARB), and plethysmographic volume (VApleth) as clinical and physiologic severity of emphysema increases.
Primary Outcome
To test the hypothesis that DLCO SB underestimates DLCO derived by the re-breathe DLCO maneuver, and that VA SB similarly underestimates VA RB. Alveolar volume derived with the two maneuvers will be compared with body plethysmography, the gold standard of total lung volume measurement in patients with emphysema.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2006-01 |
| Est. Completion | 2008-07 |
What the finished NCT00528944 record still lists
NCT00528944 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 73 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00528944 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00528944 about?
NCT00528944 is a clinical study titled "Single-Breath Measurement Underestimates Ventilatory Volume According to Emphysema Severity". Although single breath helium (He) dilution measurement (VASB) is currently used in pulmonary function laboratories to assess functional alveolar volume and diffusing capacity for carbon monoxide, the extent to which VASB reflects ventilatory and thoracic volume has not been prospectively determined...
What is the current status of trial NCT00528944?
This trial is currently completed. The enrollment target is 73 participants. The study started on 2006-01. Estimated completion is 2008-07.
Who is sponsoring clinical trial NCT00528944?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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