Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 9 of 10

COMPLETED NA

Nutrition Study for School Age Children

NCT00620152

TERMINATED Phase 2

Trial of Lovaza in Adolescents With Mild to Moderately Elevated Triglycerides

NCT00672633

COMPLETED

Allergens in Inner-City Schools and Childhood Asthma

NCT01756391

COMPLETED Phase 4

Pilot Study for Patients With Poor Response to Deferasirox

NCT00749515

COMPLETED NA

Mentored Clinical Career Award in Adolescent Substance Abuse

NCT00622219

COMPLETED Phase 1

COPE Intervention for Parents of Children With Epilepsy

NCT00767026

TERMINATED NA

Vitamin D Levels in Children With IBD

NCT00621257

COMPLETED

Parents at the Center: Information Management in ADHD - Clinical Trial

NCT00543257

COMPLETED

Structure and Function of Salivary Proteins

NCT00916682

COMPLETED

Impact of Immunosuppression in IBD Patients on Response to Influenza Vaccine

NCT00542776

COMPLETED NA

Testing a Personally Controlled Health Record to Ameliorate Influenza at MIT

NCT00531700

COMPLETED

iPod and Other MP3 Players on ICDs and Pacemakers in Children

NCT00542854

COMPLETED

Microbial Community Composition and Dynamics in Lungs of Cystic Fibrosis Sibling Pairs

NCT00590330

COMPLETED NA

Young Parents Program, Project Connect

NCT01379924

COMPLETED Phase 2

The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial

NCT00474851

COMPLETED Phase 1

Cholestasis Prevention: Efficacy of IV Fish Oil

NCT00512629

COMPLETED NA

Effects of a Low Glycemic Load Diet on Fatty Liver in Children

NCT00480922

TERMINATED NA

Nutritional Treatment of Overweight Adolescents With Cardiovascular Risk Factors (PowerUp)

NCT00477477

COMPLETED

Iron Overload in Stem Cell Transplant Recipients

NCT00806715

COMPLETED NA

A Low Glycemic Load Diet During Pregnancy in Overweight Women

NCT00364403

COMPLETED

Medical Office Intervention for Adolescent Drug Use - Attention Study Supplement

NCT00593034

COMPLETED NA

Study Investigating the Use of Intravenous Fluids With Dextrose for Dehydrated Children

NCT01343758

COMPLETED Phase 1

Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education

NCT00612482

COMPLETED Phase 1

Amiloride Solution and Tobramycin Solution for Inhalation for the Eradication of Burkholderia Dolosa in Patients With Cystic Fibrosis

NCT00547053

COMPLETED NA

SPECS: Safe Pediatric Euglycemia in Cardiac Surgery

NCT00443599

COMPLETED NA

Generic vs. Name-Brand Levothyroxine

NCT00403390

COMPLETED Phase 4

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants

NCT00756600

COMPLETED NA

Reducing Sugar-sweetened Beverage Consumption in Overweight Adolescents

NCT00381160

TERMINATED Phase 1

Nesiritide Use Following Cardiac Surgery in Infants

NCT00281671

COMPLETED NA

Popular Diets Study

NCT00315354

COMPLETED NA

A Randomized Controlled Trial of a School Disinfection and Hand Hygiene Program

NCT00514670

COMPLETED

Characterization of Angelman Syndrome

NCT00296764

COMPLETED NA

Screening and Brief Advice to Reduce Teen Substance Use

NCT00227877

COMPLETED NA

Electronic Health Records for Health Promotion

NCT00142077

COMPLETED

TSH Receptor Antibody Heterogeneity in Children and Adolescents With Graves' Disease

NCT00335062

COMPLETED NA

Fast Food Feeding in Youth

NCT00121706

COMPLETED

ParentLink: Better and Safer Emergency Care for Children

NCT00457600

COMPLETED NA

Reforming Pediatric Procedural Training

NCT00115596

TERMINATED Phase 2

Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis

NCT00142051

COMPLETED

Study to Identify Non-Invasive Markers of Gastrointestinal Allergy

NCT00272818

COMPLETED Phase 1

Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia

NCT00272857

COMPLETED

Inflammatory Profiles of Children at High Risk for Atherosclerosis

NCT00115232

COMPLETED NA

An 18-month Trial of a Low Glycemic Load Diet

NCT00130299

COMPLETED Phase 2

Medical Office Intervention for Adolescent Drug Use

NCT00229983

COMPLETED Phase 2

Adrenal and Gonadal Hormone Replacement in Anorexia Nervosa

NCT00310791

COMPLETED NA

Comparison of Two Pulmonary Valve Replacement Methods to Treat Tetralogy of Fallot

NCT00112320

COMPLETED NA

Trial of Cardiac Magnetic Resonance Imaging (MRI) Versus Cardiac Catheterization Prior to Glenn Operation

NCT00112424

COMPLETED NA

Nasal Calcitonin in the Treatment of Bone Mineral Loss in Children and Adolescents With Inflammatory Bowel Disease

NCT00114803

COMPLETED Phase 4

Effect of Immediate Hemoglobin A1c on Glycemic Control in Children With Type I Diabetes Mellitus

NCT00898534

COMPLETED NA

Glycemic Index and CVD: a Crossover Feeding Study

NCT00141076

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.