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NCT00281671 · ClinicalTrials.gov registry record · Phase 1
Nesiritide Use Following Cardiac Surgery in Infants
A Phase 1 study, sponsored by Boston Children's Hospital.
- Terminated
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT00281671: Clinical Trial Phase 1 study, sponsored by Boston Children's Hospital.
NCT00281671 is a Phase 1 study that was terminated before completion, run by Boston Children's Hospital. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00281671, a Phase 1 study, was terminated before completion, sponsored by Boston Children's Hospital.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effects of nesiritide on urine output and hemodynamics following cardiopulmonary bypass in infants. Safety and pharmacokinetic data will also be obtained.
Primary Outcome
Urine output measured in cc/kg/hour during the last 5 hours of the study drug infusion
Interventions
- DRUG Placebo
- DRUG nesiritide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2006-04-08 |
| Est. Completion | 2008-10 |
| Phase | Phase 1 |
Why NCT00281671 stopped before completion
NCT00281671 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00281671 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00281671 about?
NCT00281671 is a clinical study titled "Nesiritide Use Following Cardiac Surgery in Infants". The purpose of this study is to determine the effects of nesiritide on urine output and hemodynamics following cardiopulmonary bypass in infants. Safety and pharmacokinetic data will also be obtained.
What is the current status of trial NCT00281671?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2006-04-08. Estimated completion is 2008-10.
What interventions are being tested in trial NCT00281671?
The interventions under investigation include: Placebo (DRUG), nesiritide (DRUG).
Who is sponsoring clinical trial NCT00281671?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00281671's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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