Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 8 of 10

COMPLETED

Electrical Impedance Myography and Ultrasound as Biomarkers of Duchenne Muscular Dystrophy

NCT01491555

COMPLETED Phase 3

Heart And Lung Failure - Pediatric INsulin Titration Trial

NCT01565941

COMPLETED NA

Family-based Crisis Intervention With Suicidal Adolescents in the ED

NCT02610309

COMPLETED NA

Closed-Loop Insulin Delivery in Children Less Than 7 Years of Age

NCT01421225

TERMINATED Phase 3

Comparing Safety and Efficacy of Dexmedetomidine and Propofol

NCT01152021

COMPLETED NA

The Online Advocate: Health Related Social Problems And Diet Quality Pilot Study

NCT01374815

COMPLETED NA

FITT Exercise Counseling With Interactive Accelerometry and Physical Activity in Adolescents at Increased Risk of Early Cardiovascular Disease: A Pilot Study

NCT01394705

COMPLETED

Regional Distribution Differences Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation

NCT01504373

TERMINATED

The Pharmacokinetics of Dexmedetomidine in Children

NCT00909935

COMPLETED NA

Beverages and Societal Health

NCT01295671

COMPLETED NA

A Novel Diet-Phenotype Interaction Affecting Body Weight

NCT01303757

TERMINATED NA

Use of a Loading Dose of Vancomycin in Pediatric Dosing

NCT01290237

TERMINATED NA

Think AHEAD (A Healthy Eating And Drinking) Study

NCT01044134

COMPLETED Phase 1

Treatment of Rett Syndrome With rhIGF-1 (Mecasermin [rDNA]Injection)

NCT01253317

COMPLETED NA

Oral Zinc for the Treatment of Acute Diarrhea in US Children

NCT01198587

COMPLETED Phase 1

Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use

NCT00907309

COMPLETED NA

Dental Fear Among Children With Autism Spectrum Disorders

NCT01784276

COMPLETED NA

IIPE-PRIS Accelerating Safe Signouts

NCT02403466

COMPLETED NA

Effects of a Food Preservative on Glucose Homeostasis

NCT01179945

TERMINATED NA

A Cooking and Eating Study

NCT01079845

COMPLETED NA

Study of Adolescent Immunization Recall Systems

NCT01390363

TERMINATED NA

Cranial Cup Use for the Prevention of Positional Head Shape Deformity in the NICU

NCT01218087

COMPLETED Phase 3

Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children

NCT01044030

TERMINATED Phase 4

Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma

NCT01070888

TERMINATED

Substudy of Change in Cardiometabolic Disease (CMD) Risk Factors During an Interactive Fitness Program

NCT01080339

COMPLETED

Pharmacokinetics of Tranexamic Acid (TXA) in Children Undergoing Repair of Congenital Heart Defects Utilizing Cardiopulmonary Bypass

NCT01045356

COMPLETED

Cardiac Function as Measured by Non-invasive Electrical Velocimetry Cardiac Monitor in Hospitalized Children

NCT01030445

COMPLETED NA

Postoperative Pain After Pediatric Umbilical Hernia Repair

NCT01015053

COMPLETED Phase 2

Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT

NCT01012492

TERMINATED Phase 1

Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita

NCT01001598

COMPLETED

Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation

NCT01001533

COMPLETED

Microbial Community Composition and Metabolism in Cystic Fibrosis

NCT00954018

COMPLETED

The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study

NCT01040988

COMPLETED NA

Implementing a Comprehensive Handoff Program to Improve Pediatric Patient Safety

NCT01134419

COMPLETED

Precise Measurement of Pediatric Defibrillation Thresholds

NCT01043562

TERMINATED NA

The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine

NCT00930046

COMPLETED NA

Effect Of Biomechanical Stimulation On Skeletal Health In Adolescent And Young Women With Anorexia Nervosa

NCT01100567

COMPLETED Phase 2

A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

NCT00879034

COMPLETED Early Phase 1

Xolair Treatment for Milk Allergic Children

NCT00968110

COMPLETED NA

Using Non-Fluoroscopic Imaging Devices to Decrease Radiation Exposure During Ablation of Supraventricular Tachycardia

NCT00979303

COMPLETED Phase 1

Study on Tolerability of Levodopa/Carbidopa in Children With Angelman Syndrome

NCT00829439

COMPLETED NA

Randomized Trial of Casting Techniques for Displaced Forearm Fractures

NCT00823823

COMPLETED NA

Vitamin D Supplementation in Healthy Adolescents

NCT01126671

COMPLETED NA

Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury

NCT00830284

COMPLETED Phase 1

Pilot Study Using Avastin and Gleevec to Treat the Progression of Intraluminal Pulmonary Vein Stenosis

NCT00891527

COMPLETED NA

A Randomized Controlled Trial of Students for Nutrition and eXercise

NCT01914471

COMPLETED NA

Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive Therapy

NCT00727636

TERMINATED Phase 4

The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain

NCT00472186

COMPLETED Phase 2

Dexamethasone Treatment of Congenital Adrenal Hyperplasia

NCT00621985

COMPLETED

Infant Transition From Car Bed to Car Safety Seat

NCT00953316

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.