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NCT01112293 · ClinicalTrials.gov registry record · Phase 2

Anti-TGF Monoclonal Antibody (GC1008) in Relapsed Malignant Pleural Mesothelioma

A Phase 2 study of Pleural Malignant Mesothelioma, sponsored by Abramson Cancer Center at Penn Medicine.

Completed
Registry status
Phase 2
Development phase
14
Enrollment target
1
Study location

NCT01112293 is a Phase 2 study of Pleural Malignant Mesothelioma that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 14 participants, below the 64-participant average among 4 other Pleural Malignant Mesothelioma trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01112293, a Phase 2 study of Pleural Malignant Mesothelioma, has completed, sponsored by Abramson Cancer Center at Penn Medicine.

COMPLETED
Registry status
Phase 2
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

This study is being conducted to evaluate the overall safety and effectiveness of an investigational drug, GC1008, in patients with mesothelioma. An investigational drug is one that has not been approved by the FDA. Approximately 40 people will be enrolled on this study at the University of Pennsylvania (Main Institution/Coordinating Site) and the University of Chicago (Participating Institution). We expect about 20 subjects to be enrolled at each institution.

Interventions

  • DRUG GC1008

Study Locations (1)

Pennsylvania

  • Abramson Cancer Center of the University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2010-04
Est. Completion 2014-12
Phase Phase 2

What the Registry Record Tells You About NCT01112293

The ClinicalTrials.gov registry entry for NCT01112293 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 64-participant average among 4 other Pleural Malignant Mesothelioma trials with a reported enrollment target (78% lower). The listed sponsor is Abramson Cancer Center at Penn Medicine, which has 402 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pleural Malignant Mesothelioma appearing as the primary indexed condition, and to 1 intervention - of which GC1008 is the first listed.

NCT01112293 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT01112293 about?

NCT01112293 is a clinical study titled "Anti-TGF Monoclonal Antibody (GC1008) in Relapsed Malignant Pleural Mesothelioma". This study is being conducted to evaluate the overall safety and effectiveness of an investigational drug, GC1008, in patients with mesothelioma. An investigational drug is one that has not been approved by the FDA. Approximately 40 people will be enrolled on this study at the University of Pennsylv...

What is the current status of trial NCT01112293?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2010-04. Estimated completion is 2014-12.

What conditions does trial NCT01112293 study?

This clinical trial studies the following conditions: Pleural Malignant Mesothelioma.

What interventions are being tested in trial NCT01112293?

The interventions under investigation include: GC1008 (DRUG).

Who is sponsoring clinical trial NCT01112293?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01112293 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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